2-((tert-Butyldiphenylsilyl)oxy)acetic acid

Modify Date: 2025-08-23 18:13:17

2-((tert-Butyldiphenylsilyl)oxy)acetic acid Structure
2-((tert-Butyldiphenylsilyl)oxy)acetic acid structure
Common Name 2-((tert-Butyldiphenylsilyl)oxy)acetic acid
CAS Number 76271-74-4 Molecular Weight 314.451
Density 1.1±0.1 g/cm3 Boiling Point 395.1±34.0 °C at 760 mmHg
Molecular Formula C18H22O3Si Melting Point N/A
MSDS N/A Flash Point 192.8±25.7 °C

 Names

Name 2-[tert-butyl(diphenyl)silyl]oxyacetic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 395.1±34.0 °C at 760 mmHg
Molecular Formula C18H22O3Si
Molecular Weight 314.451
Flash Point 192.8±25.7 °C
Exact Mass 314.133820
PSA 46.53000
LogP 5.99
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.554
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synthetic Route

~94%

2-((tert-Butyldiphenylsilyl)oxy)acetic acid Structure

2-((tert-Butyld...

CAS#:76271-74-4

Literature: Ascenso, Osvaldo S.; Marques, Joao C.; Santos, Ana Rita; Xavier, Karina B.; Rita Ventura; Maycock, Christopher D. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 3 p. 1236 - 1241

~79%

2-((tert-Butyldiphenylsilyl)oxy)acetic acid Structure

2-((tert-Butyld...

CAS#:76271-74-4

Literature: Nicolaou; Snyder, Scott A.; Huang, Xianhai; Simonsen, Klaus B.; Koumbis, Alexandros E.; Bigot, Antony Journal of the American Chemical Society, 2004 , vol. 126, # 32 p. 10162 - 10173

~87%

2-((tert-Butyldiphenylsilyl)oxy)acetic acid Structure

2-((tert-Butyld...

CAS#:76271-74-4

Literature: Fanjul, Sandra; Hulme, Alison N. Journal of Organic Chemistry, 2008 , vol. 73, # 24 p. 9788 - 9791

~88%

2-((tert-Butyldiphenylsilyl)oxy)acetic acid Structure

2-((tert-Butyld...

CAS#:76271-74-4

Literature: Banker, Pierette; Cadilla, Rodolfo; Lambert lll, Millard Hurst; Rafferty, Stephen William; Sternbach, Daniel David; Sznaidman, Marcos Luis Patent: US2004/72838 A1, 2004 ; US 20040072838 A1

~%

2-((tert-Butyldiphenylsilyl)oxy)acetic acid Structure

2-((tert-Butyld...

CAS#:76271-74-4

Literature: Craig, Donald; Ford, Mark J.; Gordon, Richard S.; Stones, James A.; White, Andrew J. P.; Williams, David J. Tetrahedron, 1999 , vol. 55, # 52 p. 15045 - 15066

 Synonyms

t-butyldiphenylsilyloxyacetic acid
2-(tert-butyl diphenylsilyloxy)acetic acid
{[tert-Butyl(diphenyl)silyl]oxy}acetic Acid
Acetic acid, 2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-
Acetic acid,[[(1,1-dimethylethyl)diphenylsilyl]oxy]
2-((t-butyldiphenylsilyl)oxy)acetic acid
{[(2-Methyl-2-propanyl)(diphenyl)silyl]oxy}acetic acid
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