Polyphyllin II

Modify Date: 2025-08-20 04:36:30

Polyphyllin II Structure
Polyphyllin II structure
Common Name Polyphyllin II
CAS Number 76296-72-5 Molecular Weight 871.016
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C44H70O16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Polyphyllin II


Polyphyllin II is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest[1].

 Names

Name Polyphyllin B
Synonym More Synonyms

 Polyphyllin II Biological Activity

Description Polyphyllin II is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest[1].
Related Catalog
References

[1]. Wang W, et al. Apoptosis in HepaRG and HL-7702 cells inducted by polyphyllin II through caspases activation and cell-cycle arrest. J Cell Physiol. 2019 May;234(5):7078-7089.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C44H70O16
Molecular Weight 871.016
Exact Mass 870.461304
PSA 255.91000
LogP 6.02
Index of Refraction 1.628
InChIKey AWKXNOOUWFJCMU-WMRBLUSKSA-N
SMILES CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(OC7OC(CO)C(O)C7O)C(OC7OC(C)C(O)C(O)C7O)C6O)CCC5(C)C4CCC3(C)C1C2C

 Safety Information

Safety Phrases 24/25
HS Code 29389090

 Synonyms

(3β,25R)-17-Hydroxyspirost-5-en-3-yl α-L-arabinofuranosyl-(1->4)-[6-deoxy-α-L-mannopyranosyl-(1->3)]-β-D-glucopyranoside
PolyphyllinD
N1953
Polyphyllin II
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