3β-Acetoxy-hop-22(29)-ene

Modify Date: 2024-01-14 11:09:05

3β-Acetoxy-hop-22(29)-ene Structure
3β-Acetoxy-hop-22(29)-ene structure
Common Name 3β-Acetoxy-hop-22(29)-ene
CAS Number 76582-61-1 Molecular Weight 468.75
Density N/A Boiling Point N/A
Molecular Formula C32H52O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3β-Acetoxy-hop-22(29)-ene


3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear[1].

 Names

Name 3β-Acetoxy-hop-22(29)-ene

 3β-Acetoxy-hop-22(29)-ene Biological Activity

Description 3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear[1].
Related Catalog
Target

IC50: 0.23 μmol/ear (MPO), 5.74 ± 0.49 μM (yeast α-glucosidase)[1]

References

[1]. López-Huerta FA, et al. Hopane-type triterpenes from Cnidoscolus spinosus and their bioactivities. Bioorg Chem. 2020 Jul;100:103919.

 Chemical & Physical Properties

Molecular Formula C32H52O2
Molecular Weight 468.75