Detomidine
Modify Date: 2024-01-06 20:27:19
Detomidine structure
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Common Name | Detomidine | ||
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| CAS Number | 76631-46-4 | Molecular Weight | 186.25300 | |
| Density | 1.077 g/cm3 | Boiling Point | 386.5ºC at 760 mmHg | |
| Molecular Formula | C12H14N2 | Melting Point | 160ºC | |
| MSDS | N/A | Flash Point | 200.6ºC | |
Use of DetomidineDetomidine produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonistTarget: α2-adrenergic agonistDetomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under the trade name Dormosedan. Currently, detomidine is only licenced for use in horses.Detomidine is a sedative with analgesic properties. α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action. |
| Name | 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole |
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| Synonym | More Synonyms |
| Description | Detomidine produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonistTarget: α2-adrenergic agonistDetomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under the trade name Dormosedan. Currently, detomidine is only licenced for use in horses.Detomidine is a sedative with analgesic properties. α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action. |
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| Related Catalog | |
| References |
| Density | 1.077 g/cm3 |
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| Boiling Point | 386.5ºC at 760 mmHg |
| Melting Point | 160ºC |
| Molecular Formula | C12H14N2 |
| Molecular Weight | 186.25300 |
| Flash Point | 200.6ºC |
| Exact Mass | 186.11600 |
| PSA | 28.68000 |
| LogP | 2.61730 |
| Index of Refraction | 1.582 |
| HS Code | 2933290090 |
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| HS Code | 2933290090 |
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| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| detomidine |
| unii-7n8k34p2xh |