Amino-PEG6-amine

Modify Date: 2024-01-05 16:19:58

Amino-PEG6-amine Structure
Amino-PEG6-amine structure
Common Name Amino-PEG6-amine
CAS Number 76927-70-3 Molecular Weight 324.41400
Density N/A Boiling Point N/A
Molecular Formula C14H32N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG6-amine


Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name peoda7
Synonym More Synonyms

 Amino-PEG6-amine Biological Activity

Description Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.

 Chemical & Physical Properties

Molecular Formula C14H32N2O6
Molecular Weight 324.41400
Exact Mass 324.22600
PSA 107.42000
LogP 0.40400
Storage condition 2-8°C

 Synonyms

O,O'-bis(2-aminoethyl)pentaethylene glycol
1,20-Diamino-3,6,9,12,15,18-hexaoxaeicosane
2-{2-[2-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethylamine
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