methsuximide

Modify Date: 2026-07-16 17:17:17

methsuximide structure	Common Name	methsuximide
	CAS Number	77-41-8	Molecular Weight	203.23700
	Density	1.59g/cm3	Boiling Point	489.2ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₃NO₂	Melting Point	52-53°
	MSDS	N/A	Flash Point	191.7ºC
	Symbol	GHS07	Signal Word	Warning

Use of methsuximide

Methsuximide is an anticonvulsant agent. Methsuximide is effective in petit mal, psychomotor and focal motor attacks[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	1,3-dimethyl-3-phenylpyrrolidine-2,5-dione
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Methsuximide is an anticonvulsant agent. Methsuximide is effective in petit mal, psychomotor and focal motor attacks[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. MARY LOUISE SCHOLL, et al. Celontin - a New Anticonvulsant.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.59g/cm3
Boiling Point	489.2ºC at 760 mmHg
Melting Point	52-53°
Molecular Formula	C₁₂H₁₃NO₂
Molecular Weight	203.23700
Flash Point	191.7ºC
Exact Mass	203.09500
PSA	37.38000
LogP	1.27090
Index of Refraction	1.692
InChIKey	AJXPJJZHWIXJCJ-UHFFFAOYSA-N
SMILES	CN1C(=O)CC(C)(c2ccccc2)C1=O
Storage condition	Refrigerator

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WN2625000

CHEMICAL NAME :: Succinimide, N,2-dimethyl-2-phenyl-

CAS REGISTRY NUMBER :: 77-41-8

BEILSTEIN REFERENCE NO. :: 0168315

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H13-N-O2

MOLECULAR WEIGHT :: 203.26

WISWESSER LINE NOTATION :: T5VNVTJ B1 D1 DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 6,740,1954 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 1006 mg/kg

SEX/DURATION :: female 8-10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 38,438,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6158 No. of Facilities: 29 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 876 (estimated) No. of Female Employees: 408 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H412
Precautionary Statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

(+/-)-2-Methyl-...

CAS#:14231-67-5

methylamine

CAS#:74-89-5

methsuximide

CAS#:77-41-8

Learn More

Literature: Vystrcil; Cerny Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 804,807 Show Details Miller; Long Journal of the American Chemical Society, 1951 , vol. 73, p. 4895,4897

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 2
CAS#:14231-67-5 (+/-)-2-Methyl-... CAS#:74-89-5 methylamine
DownStream 1
CAS#:39122-23-1 (3S)-1,3-dimeth...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green ...
Source: NCGC
Target: N/A
External Id: Ebola screen2_EMI141217_green

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 blue c...
Source: NCGC
Target: N/A
External Id: Ebola screen1_EMI141217blue

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 ratio ...
Source: NCGC
Target: N/A
External Id: Ebola screen1_EMI141217_ratio

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen1 green c...
Source: NCGC
Target: N/A
External Id: Ebola screen1_EMI141217_green

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio ...
Source: NCGC
Target: N/A
External Id: Ebola screen2_EMI141217_ratio

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue c...
Source: NCGC
Target: N/A
External Id: Ebola screen2_EMI141217_blue

Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, blue c...
Source: NCGC
Target: N/A
External Id: Ebola screen1_EM141217_blue

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Celontin

1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dion

1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione

mesuximid

Mesuximide

Mesuximida

Metsuccimide

Petinutin

methsuximide

Methsuximid

Mesuximidum

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: SMILES notation of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is CN1C(=O)CC(C)(c2ccccc2)C1=O.

Q: What is the polar surface area (PSA) of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: Polar surface area (PSA) of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is 37.38000.

Q: What is the CAS number of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: CAS number of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is 77-41-8.

Q: What is the English name of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: The English name of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione.

Q: What English synonyms does 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione have?

A: English synonyms of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione: Celontin, 1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dion, 1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione, mesuximid, Mesuximide, Mesuximida, Metsuccimide, Petinutin, methsuximide, Methsuximid, Mesuximidum.

Q: What are the storage conditions for 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: Storage conditions for 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione: Refrigerator.

Q: What are the downstream products of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: Related downstream products(CAS) of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione: 39122-23-1.

Q: What is the LogP of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: LogP of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is 1.27090.

Q: What is the boiling point of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: Boiling point of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is 489.2ºC at 760 mmHg.

Q: What is the molecular weight of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione?

A: Molecular weight of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione is 203.23700.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: methsuximide
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: mesuximide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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