4-Phenylpiperidine
4-Phenylpiperidine structure
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Common Name | 4-Phenylpiperidine | ||
|---|---|---|---|---|
| CAS Number | 771-99-3 | Molecular Weight | 161.243 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 259.9±29.0 °C at 760 mmHg | |
| Molecular Formula | C11H15N | Melting Point | 61-65 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 113.0±19.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Phenylpiperidine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 259.9±29.0 °C at 760 mmHg |
| Melting Point | 61-65 °C(lit.) |
| Molecular Formula | C11H15N |
| Molecular Weight | 161.243 |
| Flash Point | 113.0±19.7 °C |
| Exact Mass | 161.120453 |
| PSA | 12.03000 |
| LogP | 2.39 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.522 |
| InChIKey | UTBULQCHEUWJNV-UHFFFAOYSA-N |
| SMILES | c1ccc(C2CCNCC2)cc1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37/39-S45-S37/39-S36/37 |
| RIDADR | UN 2922 8/PG 2 |
| WGK Germany | 3 |
| RTECS | TM2625000 |
| HS Code | 2933399090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 10 | |
CAS#:38025-45-5
CAS#:123387-49-5
CAS#:43064-12-6
CAS#:84473-59-6
CAS#:939-23-1
CAS#:51304-58-6
CAS#:10338-69-9
CAS#:14149-31-6
CAS#:62143-51-5
CAS#:15037-36-2
CAS#:80980-89-8
CAS#:31414-54-7
CAS#:14446-73-2
CAS#:136534-70-8
CAS#:26905-03-3
CAS#:1254977-87-1
CAS#:120447-45-2
CAS#:16168-22-2
CAS#:774-52-7This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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A strategy for isotope containment during radiosynthesis--devolatilisation of bromobenzene by fluorous-tagging-Ir-catalysed borylation en route to the 4-phenylpiperidine pharmacophore.
Org. Biomol. Chem. 6 , 4093-4095, (2008) Syntheses of two 4-phenylpiperidines from bromobenzene have been developed involving anchoring to a fluorous-tag, Ir-catalysed borylation, Pd- and Co-catalysed elaboration then traceless cleavage. Alt... |
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Structure-activity studies of morphine fragments. I. 4-alkyl-4-(m-hydroxy-phenyl)-piperidines.
Mol. Pharmacol. 34(3) , 363-76, (1988) The 4-(m-OH-phenyl)piperidines are a flexible fragment of the morphine/benzomorphan fused-ring opioids. Analogs in this family were synthesized with varying 4-alkyl substituents increasing in bulk fro... |
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Radical-mediated nitrile translocation as the key step in the stereoselective transformation of 2-(4-chloro-2-cyanobutyl)aziridines to methyl cis-(1-arylmethyl-4-phenylpiperidin-2-yl)acetates.
Org. Biomol. Chem. 10(16) , 3308-14, (2012) Non-activated 2-(4-chloro-2-cyano-2-phenylbutyl)aziridines were used as building blocks for the stereoselective synthesis of novel cis-2-cyanomethyl-4-phenylpiperidines via a microwave-assisted azirid... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of active transport of [3H]acetylcholine using purified Torpedo californic...
Source: ChEMBL
Target: Vesicular acetylcholine transporter
External Id: CHEMBL636849
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Name: Hill coefficient in rat brain 5-hydroxytryptamine 1A assay
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 1A
External Id: CHEMBL841450
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Name: Compound was tested for the inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine...
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 3D
External Id: CHEMBL618129
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Name: ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3301363
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Name: Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 1A
External Id: CHEMBL615962
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Piperidine,4-phenyl |
| 4-phenylpiperazine |
| MFCD00005957 |
| 4-Ph-piperdine |
| EINECS 212-243-1 |
| 4-phenyl-piperidine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of 4-Phenylpiperidine? |
| A: Related upstream materials(CAS) of 4-Phenylpiperidine: 38025-45-5;123387-49-5;43064-12-6;84473-59-6;939-23-1;51304-58-6;10338-69-9;14149-31-6;62143-51-5. |
| Q: What is the InChIKey of 4-Phenylpiperidine? |
| A: InChIKey of 4-Phenylpiperidine is UTBULQCHEUWJNV-UHFFFAOYSA-N. |
| Q: What English synonyms does 4-Phenylpiperidine have? |
| A: English synonyms of 4-Phenylpiperidine: Piperidine,4-phenyl, 4-phenylpiperazine, MFCD00005957, 4-Ph-piperdine, EINECS 212-243-1, 4-phenyl-piperidine. |
| Q: What is the molecular formula of 4-Phenylpiperidine? |
| A: Molecular formula of 4-Phenylpiperidine is C11H15N. |
| Q: What is the polar surface area (PSA) of 4-Phenylpiperidine? |
| A: Polar surface area (PSA) of 4-Phenylpiperidine is 12.03000. |
| Q: What is the CAS number of 4-Phenylpiperidine? |
| A: CAS number of 4-Phenylpiperidine is 771-99-3. |
| Q: What is the molecular weight of 4-Phenylpiperidine? |
| A: Molecular weight of 4-Phenylpiperidine is 161.243. |
| Q: What is the safety information for 4-Phenylpiperidine? |
| A: Safety information for 4-Phenylpiperidine: S26-S36/37/39-S45-S37/39-S36/37. |
| Q: What are the downstream products of 4-Phenylpiperidine? |
| A: Related downstream products(CAS) of 4-Phenylpiperidine: 15037-36-2;80980-89-8;31414-54-7;14446-73-2;136534-70-8;26905-03-3;1254977-87-1;120447-45-2;16168-22-2;774-52-7. |
| Q: What is the SMILES notation of 4-Phenylpiperidine? |
| A: SMILES notation of 4-Phenylpiperidine is c1ccc(C2CCNCC2)cc1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |