(-)-6beta-Hydroxy-5beta,8beta,9beta,10alpha-cleroda-3,13-dien-16,15-olid-18-oic acid

Modify Date: 2025-09-12 08:10:36

(-)-6beta-Hydroxy-5beta,8beta,9beta,10alpha-cleroda-3,13-dien-16,15-olid-18-oic acid Structure
(-)-6beta-Hydroxy-5beta,8beta,9beta,10alpha-cleroda-3,13-dien-16,15-olid-18-oic acid structure
Common Name (-)-6beta-Hydroxy-5beta,8beta,9beta,10alpha-cleroda-3,13-dien-16,15-olid-18-oic acid
CAS Number 771493-42-6 Molecular Weight 348.43
Density 1.2±0.1 g/cm3 Boiling Point 549.8±35.0 °C at 760 mmHg
Molecular Formula C20H28O5 Melting Point N/A
MSDS N/A Flash Point 193.4±19.4 °C

 Use of (-)-6beta-Hydroxy-5beta,8beta,9beta,10alpha-cleroda-3,13-dien-16,15-olid-18-oic acid


(-)-6β-Hydroxy-5β,8β,9β,10α-cleroda-3,13-dien-16,15-olid-18-oic acid (compound 4) is a α-Glucosidase inhibitor with an IC50 value of 577.7 µM[1].

 Names

Name (4aR,5S,6R,8S,8aR)-8-hydroxy-5,6,8a-trimethyl-5-(2-(2-oxo-2,5-dihydrofuran-3-yl)ethyl)-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid
Synonym More Synonyms

  Biological Activity

Description (-)-6β-Hydroxy-5β,8β,9β,10α-cleroda-3,13-dien-16,15-olid-18-oic acid (compound 4) is a α-Glucosidase inhibitor with an IC50 value of 577.7 µM[1].
Related Catalog
Target

IC50: 577.7 µM (α-Glucosidase)[1]

References

[1]. Iqbal, et al. α-Glucosidase Inhibitory Constituents from Duranta repens. CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52(7), 785-789.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 549.8±35.0 °C at 760 mmHg
Molecular Formula C20H28O5
Molecular Weight 348.43
Flash Point 193.4±19.4 °C
Exact Mass 348.193665
PSA 83.83000
LogP 2.81
Vapour Pressure 0.0±3.4 mmHg at 25°C
Index of Refraction 1.544

 Safety Information

Hazard Codes Xi

 Synonyms

(4aS,5R,6S,8R,8aS)-8-Hydroxy-5,6,8a-trimethyl-5-[2-(2-oxo-2,5-dihydro-3-furanyl)ethyl]-3,4,4a,5,6,7,8,8a-octahydro-1-naphthalenecarboxylic acid
1-Naphthalenecarboxylic acid, 5-[2-(2,5-dihydro-2-oxo-3-furanyl)ethyl]-3,4,4a,5,6,7,8,8a-octahydro-8-hydroxy-5,6,8a-trimethyl-, (4aS,5R,6S,8R,8aS)-
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