S-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINE CARBOXYLIC ACID BENZYL ESTER P-TOLUENESULFONIC ACID SALT

Modify Date: 2024-01-02 10:32:36

S-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINE CARBOXYLIC ACID BENZYL ESTER P-TOLUENESULFONIC ACID SALT Structure
S-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINE CARBOXYLIC ACID BENZYL ESTER P-TOLUENESULFONIC ACID SALT structure
Common Name S-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINE CARBOXYLIC ACID BENZYL ESTER P-TOLUENESULFONIC ACID SALT
CAS Number 77497-97-3 Molecular Weight 439.524
Density N/A Boiling Point 634.1ºC at 760 mmHg
Molecular Formula C24H25NO5S Melting Point 145-150°C
MSDS Chinese USA Flash Point N/A
Symbol GHS09
GHS09
Signal Word

 Names

Name Benzyl (S)-(-)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate p-toluenesulfonic acid salt
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 634.1ºC at 760 mmHg
Melting Point 145-150°C
Molecular Formula C24H25NO5S
Molecular Weight 439.524
Exact Mass 439.145355
PSA 101.08000
LogP 5.09560
Storage condition 2~8°C

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: Benzyl (s)-(-)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate p-toluenesulfonic acid salt
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H411:Toxic to aquatic life with long lasting effects
P273:Avoid release to the environment

Section3. Composition/information on ingredients.
Ingredient name:Benzyl (s)-(-)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate p-toluenesulfonic acid salt
CAS number:77497-97-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C17H17NO2.C7H8O3S
Molecular weight: 439.5

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS09
GHS09
Hazard Statements H411
Precautionary Statements P273
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes N:Dangerousfortheenvironment;
Risk Phrases R51/53
Safety Phrases S61
RIDADR UN 3077
HS Code 2933499090

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Liu, L.T. et al.

Bioorg. Med. Chem. Lett. 6 , 1335, (1996)

 Synonyms

EINECS 406-960-0
THIQ-B
(S)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID BENZYL ESTER
para-toluene sulfonate salt of the benzyl ester of (S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid
benzyl (S)-(-)-1,2,3,4-tetrahydro-3-isoquinoline carboxylate p-toluenesulfonic acid salt
BENZYL(3S)-1,2,3,4-TETRAHYDRO ISOQUINOLINE-3-CARBOXYLATE
benzyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate p-toluenesulfonate
(S)-1,2,3,4-Tetrahydroisoquinoline carboxylic acid phenylmethyl ester
Benzyl-(S)-1,2,3,4-Tetrahydro-iso-Quinoline-3-Carboxylate
Benzyl (S)-(-)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylate p-To
Benzyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate 4-methylbenzenesulfonate (1:1)
(S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
MFCD03419265
benzyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate tosylate
3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, phenylmethyl ester, (3S)-, 4-methylbenzenesulfonate (1:1)
benzyl (S)-(-)-1,2,3,4-tetrahydroiso-quinolinecar
T66 CMT&J DVO1R &&S Form p-TOSOH Salt
phenylmethyl ester tosylate salt
Benzyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate 4-methylbenzenesulfonate
Benzyl-(S)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate P-Tosylate
BENZYL (3S)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLATE
Benzyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate 4-methylbenzenesulfonate (1:1)
Phenylmethyl(3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
S-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINE CARBOXYLIC ACID BENZYL ESTER P-TOLUENESULFONIC ACID SALT