Phenytoin-15n2,13c

Modify Date: 2023-05-06 15:58:51

Phenytoin-15n2,13c structure	Common Name	Phenytoin-15n2,13c
	CAS Number	78213-26-0	Molecular Weight	255.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄₁₃CH₁₂₁₅N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Phenytoin-15n2,13c

Phenytoin-15N2,13C is the 13C and 15N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].

Name	Phenytoin-15n2,13c

Description	Phenytoin-15N2,13C is the 13C and 15N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Rogawski, M.A. and W. Loscher, The neurobiology of antiepileptic drugs. Nat Rev Neurosci, 2004. 5(7): p. 553-64. [3]. Porter, R.J., et al., Mechanisms of action of antiseizure drugs. Handb Clin Neurol, 2012. 108: p. 663-81. [4]. Balaji, S., Medical therapy for sudden death. Pediatr Clin North Am, 2004. 51(5): p. 1379-87. [5]. Michaela Nelson, et al. The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis. Mol Cancer. 2015 Jan 2714(1):13.

Molecular Formula	C₁₄₁₃CH₁₂₁₅N₂O₂
Molecular Weight	255.25

Phenytoin-15n2,13c

Use of Phenytoin-15n2,13c

Names

Phenytoin-15n2,13c Biological Activity

Chemical & Physical Properties