2-Methyl-5-HT
2-Methyl-5-HT structure
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Common Name | 2-Methyl-5-HT | ||
|---|---|---|---|---|
| CAS Number | 78263-90-8 | Molecular Weight | 190.24200 | |
| Density | 1.242g/cm3 | Boiling Point | 420.9ºC at 760 mmHg | |
| Molecular Formula | C11H14N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 208.4ºC | |
Use of 2-Methyl-5-HT2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1]. |
| Name | 2-methylserotonin |
|---|---|
| Synonym | More Synonyms |
| Description | 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1]. |
|---|---|
| Target |
5-HT3 Receptor |
| In Vivo | 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1]. Animal Model: Male Sprague-Dawley rats[1] Dosage: 3 mg/kg Administration: I.p.; 45 minutes Result: Significantly decreased time of immobility thus showing anti-depressive-like effects. |
| References |
| Density | 1.242g/cm3 |
|---|---|
| Boiling Point | 420.9ºC at 760 mmHg |
| Molecular Formula | C11H14N2O |
| Molecular Weight | 190.24200 |
| Flash Point | 208.4ºC |
| Exact Mass | 190.11100 |
| PSA | 62.04000 |
| LogP | 2.38340 |
| Index of Refraction | 1.687 |
| InChIKey | WYWNEDARFVJQSG-UHFFFAOYSA-N |
| SMILES | Cc1[nH]c2ccc(O)cc2c1CCN |
| WGK Germany | 3 |
|---|---|
| HS Code | 2933990090 |
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: HERCULES TECHNOLOGY MANAGEMENT CO V, INC.; BLAGG, Julian Patent: WO2011/47156 A1, 2011 ; Location in patent: Page/Page column 71 ; WO 2011/047156 A1 |
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Ismaiel; Titeler; Miller; Smith; Glennon Journal of medicinal chemistry, 1990 , vol. 33, # 2 p. 755 - 758 |
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Ismaiel; Titeler; Miller; Smith; Glennon Journal of medicinal chemistry, 1990 , vol. 33, # 2 p. 755 - 758 |
|
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Ismaiel; Titeler; Miller; Smith; Glennon Journal of medicinal chemistry, 1990 , vol. 33, # 2 p. 755 - 758 |
|
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Baggett, Andrew W.; Cournia, Zoe; Han, Min Suk; Patargias, George; Glass, Adam C.; Liu, Shih-Yuan; Nolen, Brad J. ChemMedChem, 2012 , vol. 7, # 7 p. 1286 - 1294 |
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Baggett, Andrew W.; Cournia, Zoe; Han, Min Suk; Patargias, George; Glass, Adam C.; Liu, Shih-Yuan; Nolen, Brad J. ChemMedChem, 2012 , vol. 7, # 7 p. 1286 - 1294 |
|
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Baggett, Andrew W.; Cournia, Zoe; Han, Min Suk; Patargias, George; Glass, Adam C.; Liu, Shih-Yuan; Nolen, Brad J. ChemMedChem, 2012 , vol. 7, # 7 p. 1286 - 1294 |
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: Shaw Journal of the American Chemical Society, 1955 , vol. 77, p. 4319,4320 Journal of the American Chemical Society, 1956 , vol. 78, p. 6419 |
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2-Methyl-5-HT CAS#:78263-90-8 |
| Literature: HERCULES TECHNOLOGY MANAGEMENT CO V, INC.; BLAGG, Julian Patent: WO2011/47156 A1, 2011 ; WO 2011/047156 A1 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2-Methyl-5-HT |
| Lopac-M-109 |
| 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol |
| 2-Me 5-HT |
| 2-Methyl-5-hydroxytryptamine |
| Tocris-0558 |