2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine
Modify Date: 2025-08-26 20:56:52
2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine structure
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Common Name | 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine | ||
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| CAS Number | 78636-53-0 | Molecular Weight | 259.23 | |
| Density | 1.73 g/cm3 | Boiling Point | 495.4ºC at 760 mmHg | |
| Molecular Formula | C10H14FN3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 253.4ºC | |
Use of 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. |
| Name | 2'-fluoro-5-methylarabino-furanosylcytosine |
|---|---|
| Synonym | More Synonyms |
| Description | 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. |
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| Related Catalog | |
| References |
| Density | 1.73 g/cm3 |
|---|---|
| Boiling Point | 495.4ºC at 760 mmHg |
| Molecular Formula | C10H14FN3O4 |
| Molecular Weight | 259.23 |
| Flash Point | 253.4ºC |
| Exact Mass | 275.09200 |
| PSA | 127.70000 |
| Index of Refraction | 1.674 |
| InChIKey | QZZJZXAWLQYJFK-JVZYCSMKSA-N |
| SMILES | Cc1cn(C2OC(CO)C(O)C2F)c(=O)nc1N |
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2′-Deoxy-2′-flu... CAS#:78636-53-0 |
| Literature: Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al. Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156 |
|
~%
2′-Deoxy-2′-flu... CAS#:78636-53-0 |
| Literature: Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al. Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156 |
|
~%
2′-Deoxy-2′-flu... CAS#:78636-53-0 |
| Literature: Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al. Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156 |
|
~%
2′-Deoxy-2′-flu... CAS#:78636-53-0 |
| Literature: Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al. Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156 |
CAS#:69256-17-3|
Name: Ratio of acyclovir EC50 to compound EC50 for Macacine herpesvirus 1 isolate MJ3 infec...
Source: ChEMBL
Target: Macacine alphaherpesvirus 1
External Id: CHEMBL1220399
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|
Name: Antiherpetic activity against HSV-2
Source: ChEMBL
Target: Human alphaherpesvirus 2
External Id: CHEMBL694610
|
|
Name: Ratio of acyclovir EC50 to compound EC50 for HSV1 infected in african green monkey Ve...
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL1220397
|
|
Name: Ratio of acyclovir EC50 to compound EC50 for HSV 2 infected in african green monkey V...
Source: ChEMBL
Target: Human alphaherpesvirus 2
External Id: CHEMBL1220396
|
|
Name: Ratio of ID50/ID90 in HSV-1 in fected cells
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL850433
|
|
Name: Antiherpetic activity against HSV-1
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL883993
|
|
Name: Ratio of ID50/ID90 in HSV-2 infected cells
Source: ChEMBL
Target: Human alphaherpesvirus 2
External Id: CHEMBL850437
|
|
Name: Ratio of acyclovir EC50 to compound EC50 for Macacine herpesvirus 1 isolate A4 infect...
Source: ChEMBL
Target: Macacine alphaherpesvirus 1
External Id: CHEMBL1220407
|
|
Name: Ratio of acyclovir EC50 to compound EC50 for Macacine herpesvirus 1 isolate A5 infect...
Source: ChEMBL
Target: Macacine alphaherpesvirus 1
External Id: CHEMBL1220406
|
|
Name: Cytotoxic activity against vero cells was evaluated.
Source: ChEMBL
Target: Vero
External Id: CHEMBL821164
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| 2(1H)-Pyrimidinone,4-amino-1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-ethyl |