2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine

Modify Date: 2024-01-09 11:02:40

2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine Structure
2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine structure
Common Name 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine
CAS Number 78636-53-0 Molecular Weight 259.23
Density 1.73 g/cm3 Boiling Point 495.4ºC at 760 mmHg
Molecular Formula C10H14FN3O4 Melting Point N/A
MSDS N/A Flash Point 253.4ºC

 Use of 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine


2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 2'-fluoro-5-methylarabino-furanosylcytosine
Synonym More Synonyms

  Biological Activity

Description 2′-Deoxy-2′-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Density 1.73 g/cm3
Boiling Point 495.4ºC at 760 mmHg
Molecular Formula C10H14FN3O4
Molecular Weight 259.23
Flash Point 253.4ºC
Exact Mass 275.09200
PSA 127.70000
Index of Refraction 1.674

 Synonyms

2(1H)-Pyrimidinone,4-amino-1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-ethyl