DCLX069
Modify Date: 2024-01-17 22:59:44
DCLX069 structure
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Common Name | DCLX069 | ||
|---|---|---|---|---|
| CAS Number | 792946-69-1 | Molecular Weight | 339.431 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 515.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H25N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 265.8±30.1 °C | |
Use of DCLX069DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 µM. DCLX069 shows less active against PRMT4 and PRMT6. DCLX069 has anticancer effects[1]. |
| Name | Ethyl 3-amino-4-(4-benzyl-1-piperazinyl)benzoate |
|---|---|
| Synonym | More Synonyms |
| Description | DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 µM. DCLX069 shows less active against PRMT4 and PRMT6. DCLX069 has anticancer effects[1]. |
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| Related Catalog | |
| Target |
PRMT1:17.9 μM (IC50) |
| In Vitro | DCLX069 (12.5-100 µM) effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid leukemia cell lines (MCF7, HepG2, and THP1 cells) in a concentration-dependent manner[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 515.9±50.0 °C at 760 mmHg |
| Molecular Formula | C20H25N3O2 |
| Molecular Weight | 339.431 |
| Flash Point | 265.8±30.1 °C |
| Exact Mass | 339.194672 |
| LogP | 2.63 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.611 |
| MFCD06666140 |
| Benzoic acid, 3-amino-4-[4-(phenylmethyl)-1-piperazinyl]-, ethyl ester |
| Ethyl 3-amino-4-(4-benzyl-1-piperazinyl)benzoate |