BIBU1361

Modify Date: 2024-01-27 21:58:59

BIBU1361 Structure
BIBU1361 structure
Common Name BIBU1361
CAS Number 793726-84-8 Molecular Weight 443.95
Density N/A Boiling Point 663.5ºC at 760 mmHg
Molecular Formula C22H27ClFN7 Melting Point N/A
MSDS N/A Flash Point 355.1ºC

 Use of BIBU1361


BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].

 Names

Name N-(3-chloro-4-fluorophenyl)-6-[4-(diethylaminomethyl)piperidin-1-yl]pyrimido[5,4-d]pyrimidin-4-amine,dihydrochloride
Synonym More Synonyms

 BIBU1361 Biological Activity

Description BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].
Related Catalog
References

[1]. Ruchi Ghildiyal, et, al. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Mol Carcinog. 2013, 52,12.  

 Chemical & Physical Properties

Boiling Point 663.5ºC at 760 mmHg
Molecular Formula C22H27ClFN7
Molecular Weight 443.95
Flash Point 355.1ºC
Exact Mass 515.15300
PSA 70.07000
LogP 6.25610

 Synonyms

bibu 1361 dihydrochloride
bibu 1361
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: BIBU1361
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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