9-Oxo-10,11-dehydroageraphorone
Modify Date: 2024-01-04 22:35:22
9-Oxo-10,11-dehydroageraphorone structure
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Common Name | 9-Oxo-10,11-dehydroageraphorone | ||
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| CAS Number | 79491-71-7 | Molecular Weight | 232.32 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 373.9±42.0 °C at 760 mmHg | |
| Molecular Formula | C15H20O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 140.3±24.9 °C | |
Use of 9-Oxo-10,11-dehydroageraphoroneEuptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells[1]. |
| Name | (4R,4aS,8aR)-1-Isopropylidene-4,7-dimethyl-1,3,4,4a,5,8a-hexahydr o-2,6-naphthalenedione |
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| Synonym | More Synonyms |
| Description | Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells[1]. |
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| Related Catalog | |
| In Vitro | Euptox A (0-2 μg/mL, 48 h) 有效抑制HeLa细胞增殖[1]。 Euptox A（0-50 μg/mL，24 小时）阻止细胞周期从 S 期到 G2/M 期的转变[1]。 Euptox A 在体外以剂量依赖的方式对人肺癌 A549、HeLa 和 Hep-2 细胞系表现出显着的抗肿瘤活性[1]。 Euptox A 在体外对 S.scabiei 和P. cuniculi 表现出高度杀螨活性[1]。 |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 373.9±42.0 °C at 760 mmHg |
| Molecular Formula | C15H20O2 |
| Molecular Weight | 232.32 |
| Flash Point | 140.3±24.9 °C |
| Exact Mass | 232.146332 |
| PSA | 34.14000 |
| LogP | 2.28 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.508 |
| Hazard Codes | Xi |
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| 2,6-Naphthalenedione, 1,3,4,4a,5,8a-hexahydro-4,7-dimethyl-1-(1-methylethylidene)-, (4R,4aS,8aR)- |
| (4R,4aS,8aR)-1-Isopropylidene-4,7-dimethyl-1,3,4,4a,5,8a-hexahydro-2,6-naphthalenedione |