4-Methyl-4-(methyldisulfanyl)pentanoicacid
Modify Date: 2024-01-03 19:51:45
4-Methyl-4-(methyldisulfanyl)pentanoicacid structure
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Common Name | 4-Methyl-4-(methyldisulfanyl)pentanoicacid | ||
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| CAS Number | 796073-55-7 | Molecular Weight | 194.31500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H14O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-Methyl-4-(methyldisulfanyl)pentanoicacid4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | 4-methyl-4-(methyldisulfanyl)pentanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Molecular Formula | C7H14O2S2 |
|---|---|
| Molecular Weight | 194.31500 |
| Exact Mass | 194.04400 |
| PSA | 87.90000 |
| LogP | 2.64100 |
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~82%
4-Methyl-4-(met... CAS#:796073-55-7 |
| Literature: Zhao, Robert Yongxin; Erickson, Hans K.; Leece, Barbara A.; Reid, Emily E.; Goldmacher, Victor S.; Lambert, John M.; Chari, Ravi V. J. Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 766 - 782 |
|
~%
4-Methyl-4-(met... CAS#:796073-55-7 |
| Literature: Widdison, Wayne C.; Wilhelm, Sharon D.; Cavanagh, Emily E.; Whiteman, Kathleen R.; Leece, Barbara A.; Kovtun, Yelena; Goldmacher, Victor S.; Xie, Hongsheng; Steeves, Rita M.; Lutz, Robert J.; Zhao, Robert; Wang, Lintao; Blaettler, Walter A.; Chari, Ravi V. J. Journal of Medicinal Chemistry, 2006 , vol. 49, # 14 p. 4392 - 4408 |
| Precursor 2 | |
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| DownStream 0 | |
| 4-methyl-4-(methyldithio)pentanoic acid |
| Pentanoic acid,4-methyl-4-(methyldithio) |
| 4-methyl-4-methyldisulfanylpentanoic acid |
| 4-methyldithio-4-methyl-pentanoic acid |