Lathosterol
Lathosterol structure
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Common Name | Lathosterol | ||
|---|---|---|---|---|
| CAS Number | 80-99-9 | Molecular Weight | 386.65400 | |
| Density | 0.98 g/cm3 | Boiling Point | 479.4ºC | |
| Molecular Formula | C27H46O | Melting Point | N/A | |
| MSDS | USA | Flash Point | 208.9ºC | |
Use of LathosterolLathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 5α-cholest-7-en-3β-ol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.98 g/cm3 |
|---|---|
| Boiling Point | 479.4ºC |
| Molecular Formula | C27H46O |
| Molecular Weight | 386.65400 |
| Flash Point | 208.9ºC |
| Exact Mass | 386.35500 |
| PSA | 20.23000 |
| LogP | 7.38870 |
| Index of Refraction | 1.525 |
| InChIKey | IZVFFXVYBHFIHY-SKCNUYALSA-N |
| SMILES | CC(C)CCCC(C)C1CCC2C3=CCC4CC(O)CCC4(C)C3CCC21C |
| Storage condition | 2-8℃ |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | FZ7000000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 1 | |
CAS#:434-16-2
CAS#:6038-38-6
CAS#:16826-37-2
CAS#:57-88-5
CAS#:40823-41-4
CAS#:809-51-8
CAS#:15459-85-5
CAS#:64-17-5
CAS#:555-31-7![10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,4,5,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one structure](https://image.chemsrc.com/caspic/296/29374-80-9.png)
CAS#:29374-80-9This table lists relevant public references with title, journal and publication metadata for this compound.
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Selection of the derivatization reagent--the case of human blood cholesterol, its precursors and phytosterols GC-MS analyses.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(32) , 3806-11, (2011) Phytosterols (PS; β-sitosterol and campesterol) and cholesterol precursors (CP; desmosterol and lathosterol) have been suggested as important biochemical markers of cholesterol intestinal absorption a... |
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Serum lipid responses to weight loss differ between overweight adults with familial hypercholesterolemia and those with familial combined hyperlipidemia.
J. Nutr. 144(8) , 1219-26, (2014) The effect of weight loss on lipids differs among individuals, although whether it can modify the management of hereditary hyperlipidemias has not yet been explored. The objective of this study was to... |
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Effects of ezetimibe added to statin therapy on markers of cholesterol absorption and synthesis and LDL-C lowering in hyperlipidemic patients
Atherosclerosis 225(2) , 388-96, (2012) Objective Statins inhibit cholesterol synthesis but can upregulate cholesterol absorption, with higher doses producing larger effects. Ezetimibe inhibits cholesterol absorption but also upregulates sy... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B1
External Id: CHEMBL3039488
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Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
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Name: Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B3
External Id: CHEMBL3039491
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Name: Induction of sterol accumulation in human HL60 cells at 0.1 uM incubated for 24 hrs b...
Source: ChEMBL
Target: HL-60
External Id: CHEMBL4134394
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Name: Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening
Source: 11827
Target: Phosphogluconate dehydrogenase
External Id: 6PGD_Inhibitor_Screening_2015_09
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Cholest-7-en-3beta-ol |
| Cholest-7-en-3-ol |
| 5alpha-Cholest-7-en-3beta-ol |
| (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| 5alpha-cholest-7-en-3beta-ol |
| 7-cholestenol |
| Lathosterol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of 5α-cholest-7-en-3β-ol? |
| A: CAS number of 5α-cholest-7-en-3β-ol is 80-99-9. |
| Q: What is the English name of 5α-cholest-7-en-3β-ol? |
| A: The English name of 5α-cholest-7-en-3β-ol is 5α-cholest-7-en-3β-ol. |
| Q: What is the Chinese name of 80-99-9? |
| A: Chinese name of 80-99-9 is 5α-cholest-7-en-3ß-ol. |
| Q: What is the LogP of 5α-cholest-7-en-3β-ol? |
| A: LogP of 5α-cholest-7-en-3β-ol is 7.38870. |
| Q: What are the upstream materials of 5α-cholest-7-en-3β-ol? |
| A: Related upstream materials(CAS) of 5α-cholest-7-en-3β-ol: 434-16-2;6038-38-6;16826-37-2;57-88-5;40823-41-4;809-51-8;15459-85-5;64-17-5;555-31-7. |
| Q: What is the boiling point of 5α-cholest-7-en-3β-ol? |
| A: Boiling point of 5α-cholest-7-en-3β-ol is 479.4ºC. |
| Q: What are the downstream products of 5α-cholest-7-en-3β-ol? |
| A: Related downstream products(CAS) of 5α-cholest-7-en-3β-ol: 29374-80-9. |
| Q: What English synonyms does 5α-cholest-7-en-3β-ol have? |
| A: English synonyms of 5α-cholest-7-en-3β-ol: Cholest-7-en-3beta-ol, Cholest-7-en-3-ol, 5alpha-Cholest-7-en-3beta-ol, (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol, 5alpha-cholest-7-en-3beta-ol, 7-cholestenol, Lathosterol. |
| Q: What is the polar surface area (PSA) of 5α-cholest-7-en-3β-ol? |
| A: Polar surface area (PSA) of 5α-cholest-7-en-3β-ol is 20.23000. |
| Q: What are the uses of 5α-cholest-7-en-3β-ol? |
| A: Main uses of 5α-cholest-7-en-3β-ol: Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |