AZ-1
Modify Date: 2024-08-31 07:10:48
AZ-1 structure
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Common Name | AZ-1 | ||
|---|---|---|---|---|
| CAS Number | 803735-54-8 | Molecular Weight | 430.977 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H31ClN4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZ-1AZ-1 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity; upregulates ABCA1 across multiple CNS cell types, including human astrocytes, pericytes, and microglia, through an indirect LXR mechanism and that also independently inhibit P2X7 receptor activity. |
| Name | AZ-1 |
|---|
| Description | AZ-1 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity; upregulates ABCA1 across multiple CNS cell types, including human astrocytes, pericytes, and microglia, through an indirect LXR mechanism and that also independently inhibit P2X7 receptor activity. |
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| References | References 1. Fan J, et al. J Lipid Res. 2018 May;59(5):830-842. View Related Products by Target P2X Receptor |
| Molecular Formula | C23H31ClN4O2 |
|---|---|
| Molecular Weight | 430.977 |