Notoginsenoside R1
Modify Date: 2024-01-01 17:54:04
Notoginsenoside R1 structure
|
Common Name | Notoginsenoside R1 | ||
|---|---|---|---|---|
| CAS Number | 80418-24-2 | Molecular Weight | 933.127 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1010.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C47H80O18 | Melting Point | 218 °C | |
| MSDS | Chinese USA | Flash Point | 564.9±34.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Notoginsenoside R1Notoginsenoside R1, the main bioactive component in panaxnotoginseng, is reported to have some neuronal protective, antihypertensive effects. IC50 value:Target:In vitro:In vivo: Notoginsenoside R1 significantly reduce blood pressure in spontaneously hypertensive rats and induce nitric oxide generation through increasing the phosphorylation of iNOS. Notoginsenoside R1 reduces the caudal blood pressure of spontaneously hypertensive rats through induction of iNOS regulated by long non-coding RNA AK094457 [1]. The mice with notoginsenoside R1 treatment showed significant amelioration in the cognitive function and increased choline acetyl transferase expression, as compared to the vehicle treated mice. Notoginsenoside R1 treatment inhibited Aβ accumulation and increased insulin degrading enzyme expression in both APP/PS1 mice and N2a-APP695sw cells [2]. In Notoginsenoside R1 treated rats, expression of TGF-β1and Smad3 at each time point was down-regulated, with statistical significance(P0.05) compared with that in the NDMA group [3]. |
| Name | notoginsenoside R1 |
|---|---|
| Synonym | More Synonyms |
| Description | Notoginsenoside R1, the main bioactive component in panaxnotoginseng, is reported to have some neuronal protective, antihypertensive effects. IC50 value:Target:In vitro:In vivo: Notoginsenoside R1 significantly reduce blood pressure in spontaneously hypertensive rats and induce nitric oxide generation through increasing the phosphorylation of iNOS. Notoginsenoside R1 reduces the caudal blood pressure of spontaneously hypertensive rats through induction of iNOS regulated by long non-coding RNA AK094457 [1]. The mice with notoginsenoside R1 treatment showed significant amelioration in the cognitive function and increased choline acetyl transferase expression, as compared to the vehicle treated mice. Notoginsenoside R1 treatment inhibited Aβ accumulation and increased insulin degrading enzyme expression in both APP/PS1 mice and N2a-APP695sw cells [2]. In Notoginsenoside R1 treated rats, expression of TGF-β1and Smad3 at each time point was down-regulated, with statistical significance(P0.05) compared with that in the NDMA group [3]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1010.5±65.0 °C at 760 mmHg |
| Melting Point | 218 °C |
| Molecular Formula | C47H80O18 |
| Molecular Weight | 933.127 |
| Flash Point | 564.9±34.3 °C |
| Exact Mass | 932.534485 |
| PSA | 298.14000 |
| LogP | 4.42 |
| Appearance of Characters | white to off-white |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.614 |
| Storage condition | 2-8°C |
| Water Solubility | H2O: soluble1mg/mL, clear, colorless |
|
Protective effect of panax notoginseng saponins on acute ethanol-induced liver injury is associated with ameliorating hepatic lipid accumulation and reducing ethanol-mediated oxidative stress.
J. Agric. Food Chem. 63(9) , 2413-22, (2015) The aim of present study was to evaluate the effects of Panax notoginseng saponins (PNS) against acute ethanol-induced liver injury and further to elucidate its probable mechanisms. Mice were treated ... |
|
|
A comparative study of using in-line near-infrared spectra, ultraviolet spectra and fused spectra to monitor Panax notoginseng adsorption process.
J. Pharm. Biomed. Anal. 102 , 78-84, (2014) The step of enriching and purifying saponins by macroporous resin column chromatography is closely related to the safety and efficacy of Panax notoginseng products during their manufacturing processes... |
|
|
Adulteration and cultivation region identification of American ginseng using HPLC coupled with multivariate analysis.
J. Pharm. Biomed. Anal. 99 , 8-15, (2014) American ginseng (Panax quinquefolius) is originally grown in North America. Due to price difference and supply shortage, American ginseng recently has been cultivated in northern China. Further, in t... |
| notoginsenoside Rh1 |
| Sanchinoside R1 |
| NOTOGINSENOSIDE |
| notogisenoside R1 |
| Notoginsenoside R1 |
| (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside |
| β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl- |
| ginsenoside-Rg2 |
| NotoginsenosideR1 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Notoginsenoside R1
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Notoginsenoside R1
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Notoginsenoside R1
- Price: ￥198.0/20mg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Notoginsenoside R1
- Price: $280.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Notoginsenoside R1
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
Get all suppliers and price by the below link:
Price: $111/10mM*1mLinDMSO
Reference only. check more Notoginsenoside R1 price