vitamin D3-d3

Modify Date: 2024-01-03 18:15:55

vitamin D3-d3 Structure
vitamin D3-d3 structure
Common Name vitamin D3-d3
CAS Number 80666-48-4 Molecular Weight 387.65600
Density N/A Boiling Point N/A
Molecular Formula C27H41D3O Melting Point N/A
MSDS N/A Flash Point 57.2 °F
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of vitamin D3-d3


Vitamin D3-d3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

 Names

Name vitamin D3-d3
Synonym More Synonyms

 vitamin D3-d3 Biological Activity

Description Vitamin D3-d3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Nazik Al-Hashimi, et al. Cholecalciferol;Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94(6):608-22;Hiroki Yoshioka,

 Chemical & Physical Properties

Molecular Formula C27H41D3O
Molecular Weight 387.65600
Exact Mass 387.35800
PSA 20.23000
LogP 7.61900

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H319
Precautionary Statements P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235
RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution
Flash Point(F) 57.2 °F
Flash Point(C) 14 °C

 Articles1

More Articles
Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry.

J. Chromatogr. A. 1364 , 214-22, (2014)

We have developed an ultra-high-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometric (UHPLC-APPI-MS/MS) method for the simultaneous quantitative analyses of...

 Synonyms

vitamin-d3-[2h3]