Acetyllovastatin

Modify Date: 2024-01-09 17:16:59

Acetyllovastatin structure	Common Name	Acetyllovastatin
	CAS Number	81189-92-6	Molecular Weight	446.57600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₈O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Acetyllovastatin

Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1].

Name	acetyllovastatin
Synonym	More Synonyms

Description	Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	IC50: 79 μg/mL (The enzyme acetylcholinesterase)[1]
References	[1]. Cazar, et al. Antimicrobial Butyrolactone I Derivatives from the Ecuadorian Soil Fungus Aspergillus terreus Thorn. var terreus. World Journal of Microbiology and Biotechnology, 2005,21(6-7), 1067–1075.

Molecular Formula	C₂₆H₃₈O₆
Molecular Weight	446.57600
Exact Mass	446.26700
PSA	78.90000
LogP	4.76630

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-36

N/A

CAS#:145576-24-5

2,2-DIMETHYLBUT...

CAS#:29138-64-5

~1%

Dehydrosimvastatin

CAS#:210980-68-0

N/A

CAS#:850920-00-2

Detail

Literature: DIVERSA CORPORATION Patent: WO2005/40107 A2, 2005 ; Location in patent: Page/Page column 41-43; 80-82 ;

Precursor 1
CAS#:29138-64-5 2,2-DIMETHYLBUT...
DownStream 5
CAS#:210980-68-0 Dehydrosimvastatin CAS#:145576-25-6 Acetyl simvastatin CAS#:851402-85-2 bis-simvastatin CAS#:851402-84-1 4-simvastain-8-...
CAS#:79902-63-9 Simvastatin