CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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CX5075000
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CHEMICAL NAME :
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7H-Benz(de)anthracen-7-one
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CAS REGISTRY NUMBER :
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82-05-3
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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11
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MOLECULAR FORMULA :
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C17-H10-O
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MOLECULAR WEIGHT :
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230.27
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WISWESSER LINE NOTATION :
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L C6666 1A Q IVJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1500 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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290 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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15 gm/kg/30D-I
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TOXIC EFFECTS :
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Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in erythrocyte (RBC) count
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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117 gm/kg/34W-I
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TOXIC EFFECTS :
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Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
MUTATION DATA
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TYPE OF TEST :
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Mutation in mammalian somatic cells
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TEST SYSTEM :
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Human Lymphocyte
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DOSE/DURATION :
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3300 ug/L
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,123,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.2 mg/m3 JAN 1993
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