Gomisin M2

Modify Date: 2025-08-26 19:07:36

Gomisin M2 Structure
Gomisin M2 structure
 Common Name Gomisin M2
CAS Number 82425-45-4 Molecular Weight 386.438
Density 1.2±0.1 g/cm3 Boiling Point 558.7±50.0 °C at 760 mmHg
Molecular Formula C22H26O6 Melting Point N/A
MSDS N/A Flash Point 291.7±30.1 °C

 Use of Gomisin M2


Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research[1][2].

 Names

Name (6S,7R)-1,2,3-Trimethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3', 4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-13-ol
Synonym More Synonyms

 Gomisin M2 Biological Activity

Description Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research[1][2].
Related Catalog
Target

HIV:2.4 μM (EC50)

References

[1]. Min Chen, et al. Rubrisandrins A and B, Lignans and Related anti-HIV Compounds From Schisandra Rubriflora. J Nat Prod. 2006 Dec;69(12):1697-701.

[2]. Hima Dhakal, et al. Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels. Front Pharmacol. 2019 Aug 2;10:869.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 558.7±50.0 °C at 760 mmHg
Molecular Formula C22H26O6
Molecular Weight 386.438
Flash Point 291.7±30.1 °C
Exact Mass 386.172943
PSA 66.38000
LogP 5.34
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.564

 Safety Information

Hazard Codes Xi

 Synonyms

Benzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-13-ol, 5,6,7,8-tetrahydro-1,2,3-trimethoxy-6,7-dimethyl-, (6S,7R)-
(6S,7R)-1,2,3-Trimethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-13-ol
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Chemsrc provides Gomisin M2(CAS#:82425-45-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Gomisin M2 are included as well.>> amp version: Gomisin M2

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