alpidem
alpidem structure
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Common Name | alpidem | ||
|---|---|---|---|---|
| CAS Number | 82626-01-5 | Molecular Weight | 404.34 | |
| Density | 1.24g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C21H23Cl2N3O | Melting Point | 136-138ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of alpidemAlpidem selectively binds to α1β2γ2 subunit-containing GABAA receptor with an IC50 of 17 nM and exerts anxiolytic effect[1]. |
| Name | 2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,N-dipropylacetamide |
|---|---|
| Synonym | More Synonyms |
| Description | Alpidem selectively binds to α1β2γ2 subunit-containing GABAA receptor with an IC50 of 17 nM and exerts anxiolytic effect[1]. |
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| Related Catalog | |
| References |
| Density | 1.24g/cm3 |
|---|---|
| Melting Point | 136-138ºC |
| Molecular Formula | C21H23Cl2N3O |
| Molecular Weight | 404.34 |
| Exact Mass | 403.12200 |
| PSA | 37.61000 |
| LogP | 5.49920 |
| Index of Refraction | 1.606 |
| Storage condition | Refrigerator |
| Water Solubility | DMSO: ≥10mg/mL |
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On the therapeutic action of alpidem in anxiety disorders: an overview of the European data.
Pharmacopsychiatry 23 Suppl 3 , 129-34, (1990) This review analyzes the available data on the therapeutic activity of alpidem in various anxiety syndromes. Up to now, 17 studies have been completed in Europe, dealing with a total population of mor... |
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Morphology of hepatic stellate cells in patients with fulminant or subfulminant hepatitis requiring liver transplantation.
J. Submicrosc. Cytol. Pathol. 28(1) , 5-12, (1996) Hepatic stellate cells were studied by immuno-cytochemistry with anti smooth muscle alpha-actin antibody (an activation marker for these cells) and electron microscopy, in eleven patients transplanted... |
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Studies with alpidem in normal volunteers and anxious patients.
Pharmacopsychiatry 23 Suppl 3 , 120-3, (1990) Alpidem, an imidazo-pyridine compound, has been evaluated as an anxiolytic in comparison with placebo and lorazepam. In the first of our normal volunteer studies, we compared single doses of alpidem, ... |
| ALPIDEM |
| 6-Chloro-2-(p-chlorophenyl)-N,N-dipropylimidazo(1,2-a)pyridine-3-acetamide |
| Ananxyl |
| SL 80.0342-00 |
| Alpidemum [Latin] |