Adenosine-d2

Modify Date: 2024-01-11 17:19:47

Adenosine-d2 Structure
Adenosine-d2 structure
Common Name Adenosine-d2
CAS Number 82741-17-1 Molecular Weight 269.25
Density N/A Boiling Point N/A
Molecular Formula C10H11D2N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Adenosine-d2


Adenosine-d2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

 Names

Name Adenosine-d2

 Adenosine-d2 Biological Activity

Description Adenosine-d2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625.;Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ.

 Chemical & Physical Properties

Molecular Formula C10H11D2N5O4
Molecular Weight 269.25