L-Ascorbic acid-d2

Modify Date: 2024-01-13 21:59:12

L-Ascorbic acid-d2 Structure
L-Ascorbic acid-d2 structure
Common Name L-Ascorbic acid-d2
CAS Number 82977-10-4 Molecular Weight 178.14
Density N/A Boiling Point N/A
Molecular Formula C6H6D2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Ascorbic acid-d2


L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla

 Names

Name L-Ascorbic acid-d2

 L-Ascorbic acid-d2 Biological Activity

Description L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35.;Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels

 Chemical & Physical Properties

Molecular Formula C6H6D2O6
Molecular Weight 178.14