Octreotide acetate

Modify Date: 2026-07-01 18:58:25

Octreotide acetate Structure
Octreotide acetate structure
 Common Name Octreotide acetate
CAS Number 83150-76-9 Molecular Weight 1019.239
Density 1.4±0.1 g/cm3 Boiling Point 1447.2±65.0 °C at 760 mmHg
Molecular Formula C49H66N10O10S2 Melting Point N/A
MSDS Chinese USA Flash Point 829.1±34.3 °C

 Use of Octreotide acetate


Octreotide is a somatostatin analog that binds to the somatostatin receptor, mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production.

 Names

Name Octreotide acetate
Synonym More Synonyms

 Octreotide acetate Biological Activity

Description Octreotide is a somatostatin analog that binds to the somatostatin receptor, mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production.
Related Catalog
In Vitro Octreotide reverses the PA-induced alterations in Akt and GSK3β phosphorylation and expression of GS mRNA in HepG2 cells[1].
In Vivo Octreotide significantly lowers the plasma glucose levels in the obese rats of the HFD group. Octreotide intervention significantly decreases the serum insulin concentration; however, there is no marked reduction in serum TG, TC, FFA, ALT and AST levels. Octreotide significantly inhibits the HOMA index. Octreotide decreases ipGTT and ipITT AUCs, but not significantly. Octreotide improves fat degeneration in rats with HFD-induced obesity and lipid droplet accumulation in PA-treated HepG2 cells. Octreotide promotes the phosphorylation of Akt and GSK3β and the expression of GS mRNA in rats with HFD-induced obesity[1]. Octreotide reduces body weight and wet kidney weight compared with the vehicle-treated (CONT) group. PAS and Octreotide/PAS treatment decrease cAMP levels, but Octreotide alone does not in PCK rats. In the Octreotide/PAS group, there are a significantly fewer pS6-positive cells than in the PAS alone group[2].
Animal Admin AMale PCK rats (n = 24) are assigned randomly to 1 of 4 groups (n = 6 per group): treatment by subcutaneous injection every 4 weeks treatment with 8 mg/kg Octreotide-LAR alone, 8 mg/kg PAS-LAR alone, co-application of 8 mg/kg Octreotide and 8 mg/kg PAS, or vehicle (microparticles liquid; CONT) from 4 to 16 weeks of age. The vehicle contains copolymer microparticles with polylactic-co-glycolic acid (PLGA). In 4- and 15-week-old conscious rats, heart rate (HR), diastolic blood pressure (DBP), and systolic blood pressure (SBP) are determined using a tail-cuff sphygmomanometer. Twenty-four-hour urine volume and food consumption are measured using metabolic cages after 15.5 weeks of age. After body weight measurement, the animals are anesthetized with sodium pentobarbital at 16 weeks of age, and the kidneys and liver are removed rapidly, causing lethal exsanguination. Total wet kidney weight and wet liver weight are measured, and blood samples are collected for measurements of serum urea nitrogen (SUN), aspartate amino transferase (AST), alanine aminotransferase (ALT), insulin-like growth factor-1 (IGF-1), glucose, insulin, glucagon, and cortisol.
References

[1]. Wang XX, et al. Effects of octreotide on hepatic glycogenesis in rats with high fat diet?induced obesity. Mol Med Rep. 2017 Jul;16(1):109-118

[2]. Kugita M, et al. Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease. PLoS One. 2017 May 18;12(5):e0177934.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1447.2±65.0 °C at 760 mmHg
Molecular Formula C49H66N10O10S2
Molecular Weight 1019.239
Flash Point 829.1±34.3 °C
Exact Mass 1018.440491
PSA 382.82000
LogP 0.77
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.673
InChIKey DEQANNDTNATYII-MEUDYGGUSA-N
SMILES CC(O)C(CO)NC(=O)C1CSSCC(NC(=O)C(N)Cc2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)N1
Storage condition −20°C
Water Solubility H2O: soluble

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 3004909090

 Synthetic Route

Boc-D-Phe-OH structure

Boc-D-Phe-OH

CAS#:18942-49-9

~%

Octreotide acetate Structure

Octreotide acetate

CAS#:83150-76-9

Learn More
Literature: Journal of Organic Chemistry, , vol. 68, # 3 p. 1161 - 1162

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 3004909090

 Articles155

More Articles
Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.

J. Neurosci. 34(35) , 11769-80, (2014)

Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hip...

Direct effect of incretin hormones on glucose and glycerol metabolism and hemodynamics.

Am. J. Physiol. Endocrinol. Metab. 308(5) , E426-33, (2015)

The objective of this study was to assess the insulin-independent effects of incretin hormones on glucose and glycerol metabolism and hemodynamics under euglycemic and hyperglycemic conditions. Young,...

Evaluation of cobalt-labeled octreotide analogs for molecular imaging and auger electron-based radionuclide therapy.

J. Nucl. Med. 55(8) , 1311-6, (2015)

The somatostatin receptor, which is overexpressed by many neuroendocrine tumors, is a well-known target for molecular imaging and peptide receptor radionuclide therapy. Recently, (57)Co-labeled DOTATO...

 Octreotide acetateBioassay

View more

Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
Name: Cellular viability qHTS for adrenocortical cancer (ACC) cell line SW-13
Source: NCGC
Target: N/A
External Id: ACC-ATC-p1-SW13-72hr
Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Cellular viability qHTS for adrenocortical cancer (ACC) cell line NCI-H295R
Source: NCGC
Target: N/A
External Id: ACC-ATC-p1-H295R-72hr
Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr
Name: Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H...
Source: Southern Research Institute
Target: CFTR
External Id: CF Folding
Name: Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-SARS-CoV-2-PP
Name: Agonist activity at N-terminal Flag-tagged human MRGPRX2 receptor expressed in tetrac...
Source: ChEMBL
Target: Mas-related G-protein coupled receptor member X2
External Id: CHEMBL5665199
Name: Agonist activity at N-terminal Flag-tagged human MRGPRX2 receptor expressed in tetrac...
Source: ChEMBL
Target: Mas-related G-protein coupled receptor member X2
External Id: CHEMBL5665200
Total 35, Current Page 1 of 4
1
2
3
4

 Synonyms

Octreotode Acetate
Octreotide
Sandostatin<*>
SMS 201-995
OCTREOTIDE ACETATE (GMP)
Octreotideacetate
ctreotide
H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol acetate salt (Disulfide bond)
MFCD00871400
D-Phe-Cys(1)-Phe-D-Trp-Lys-Thr-Cys(1)-N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxypropyl]-NH2
Phe-c(Cys-Phe-Trp-Lys-Thr-Cys)-CH(CH2OH)-CH(OH)-CH3
Longastatin
OXTREOTIDE
(4R,7S,10S,13R,16S,19R)-10-(4-Aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxy-2-butanyl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide
DARAMONOL
Sandostatin
Ocetreotide,Acetate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Octreotide acetate suppliers

Price: $50/1mg

Reference only. check more Octreotide acetate price

Related Compounds: More...
1-(2-Aminoethyl)cyclopropanecarbonitrile
1935919-05-3
2-[(1-Methylcyclobutyl)methyl]thiolane-2-carbaldehyde
1935577-94-8
2-(4-Methylcyclohexyl)ethanethioamide
1861159-32-1
1-[(3-methylcyclohexyl)methyl]-1H-1,2,4-triazol-3-amine
1882031-72-2
1-[(4-methylcyclohexyl)methyl]-1H-1,2,4-triazol-3-amine
1862467-07-9
2-Amino-3-(3-methylcyclohexyl)propanamide
1869211-80-2
2-Amino-3-(4-methylcyclohexyl)propanamide
1862310-70-0
n-(Propan-2-yl)-3-(trichloromethyl)-1,2,4-thiadiazol-5-amine
40145-56-0
N-Isopropyl-3-(trifluoromethyl)cyclobutan-1-amine
1863328-00-0
(3R,5R)-5-(5-ethyl-1,3,4-oxadiazol-2-yl)pyrrolidin-3-ol
1932114-41-4
Chemsrc provides Octreotide acetate(CAS#:83150-76-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Octreotide acetate are included as well.>> amp version: Octreotide acetate

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2026 ChemSrc All Rights Reserved