ILMOFOSINE

Modify Date: 2024-01-02 12:26:13

ILMOFOSINE structure	Common Name	ILMOFOSINE
	CAS Number	83519-04-4	Molecular Weight	525.76500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₅₆NO₅PS	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS06	Signal Word	Danger

Name	3-(hexadecylthio)-2-(MethoxyMethyl)propyl 2-(triMethylaMMonio)ethyl phosphate

Molecular Formula	C₂₆H₅₆NO₅PS
Molecular Weight	525.76500
Exact Mass	525.36200
PSA	102.93000
LogP	7.74150

ILMOFOSINE MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JH4758000

CHEMICAL NAME :: 3,5-Dioxa-9-thia-4-phosphapentacosan-1-aminium, 4-hydroxy-7-(methoxymethyl)-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide

CAS REGISTRY NUMBER :: 83519-04-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C26-H56-N-O5-P-S

MOLECULAR WEIGHT :: 525.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 253 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 74 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 615 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 113 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 1 mg/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,5538,1983

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301
Precautionary Statements	P301 + P310
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22
RIDADR	UN 2811 6.1/PG 3
RTECS	JH4758000

N/A

CAS#:157049-10-0

ILMOFOSINE

CAS#:83519-04-4

Literature: Reddy, Kasireddy Chandraprakash; Byun, Hoe-Sup; Bittman, Robert Tetrahedron Letters, 1994 , vol. 35, # 17 p. 2679 - 2682

ethyl α-(hexade...

CAS#:157049-09-7

ILMOFOSINE

CAS#:83519-04-4

Literature: Reddy, Kasireddy Chandraprakash; Byun, Hoe-Sup; Bittman, Robert Tetrahedron Letters, 1994 , vol. 35, # 17 p. 2679 - 2682

Phase I trial of ilmofosine as a 24 hour infusion weekly.

Invest. New Drugs 13(3) , 205-10, (1995)

Ilmofosine, an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. Maximum efficacy in preclinical models is associated with prolonged exposure to the d...

A phase II trial of ilmofosine in non-small cell bronchogenic carcinoma.

Invest. New Drugs 14(2) , 219-22, (1996)

We have conducted a study of ilmofosine (1-hexadecylthio; 2-methoxyethyl-rac-glycero-3-phosphocholine) in non-small cell bronchogenic carcinoma, using a schedule of continuous infusion for 5 days and ...

Structure-function relationships of alkyl-lysophospholipid analogs in selective antitumor activity.

Lipids 28(6) , 511-6, (1993)

This investigation was initiated in order to delineate the structure-function relationship of the anticancer alkyl-lysophospholipids and assess their degree of selective cytotoxicity toward neoplastic...

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ILMOFOSINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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ILMOFOSINE

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

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