TCL1(10-24)

Modify Date: 2024-03-12 23:40:25

TCL1(10-24) Structure
TCL1(10-24) structure
Common Name TCL1(10-24)
CAS Number 835655-37-3 Molecular Weight 1871.06
Density N/A Boiling Point N/A
Molecular Formula C88H123N23O23 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCL1(10-24)


TCL1(10-24) is a encompassing the betaA strand of human TCL1. TCL1(10-24) is a Akt inhibitor. TCL1(10-24) interacts with the Akt PH domain prevented phosphoinositide binding and hence inhibits membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis. TCL1(10-24) has tumor growth in vivo[1].

 Names

Name TCL1(10-24)

 TCL1(10-24) Biological Activity

Description TCL1(10-24) is a encompassing the betaA strand of human TCL1. TCL1(10-24) is a Akt inhibitor. TCL1(10-24) interacts with the Akt PH domain prevented phosphoinositide binding and hence inhibits membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis. TCL1(10-24) has tumor growth in vivo[1].
Related Catalog
References

[1]. Makoto Hiromura, et al. Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. J Biol Chem. 2004 Dec 17;279(51):53407-18.  

 Chemical & Physical Properties

Molecular Formula C88H123N23O23
Molecular Weight 1871.06
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