(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid

Modify Date: 2024-01-08 13:43:12

(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid Structure
(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid structure
Common Name (2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid
CAS Number 83624-01-5 Molecular Weight 245.272
Density 1.2±0.1 g/cm3 Boiling Point 362.0±42.0 °C at 760 mmHg
Molecular Formula C11H19NO5 Melting Point N/A
MSDS N/A Flash Point 172.7±27.9 °C

 Names

Name (2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 362.0±42.0 °C at 760 mmHg
Molecular Formula C11H19NO5
Molecular Weight 245.272
Flash Point 172.7±27.9 °C
Exact Mass 245.126328
PSA 76.07000
LogP -0.07
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.500

 Synthetic Route

~65%

(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid Structure

(2S,4R)-1-(tert...

CAS#:83624-01-5

Literature: Bristol-Myers Squibb Company Patent: US2007/232679 A1, 2007 ; Location in patent: Page/Page column 11 ; US 20070232679 A1

~%

(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid Structure

(2S,4R)-1-(tert...

CAS#:83624-01-5

Literature: DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1757602 A1, 2007 ;

~99%

(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid Structure

(2S,4R)-1-(tert...

CAS#:83624-01-5

Literature: Chiba, Jun; Takayama, Gensuke; Takashi, Tohru; Yokoyama, Mika; Nakayama, Atsushi; Baldwin, John J.; McDonald, Edward; Moriarty, Kevin J.; Sarko, Christopher R.; Saionz, Kurt W.; Swanson, Robert; Hussain, Zahid; Wong, Angela; MacHinaga, Nobuo Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2725 - 2746

~%

(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid Structure

(2S,4R)-1-(tert...

CAS#:83624-01-5

Literature: Chiba, Jun; Takayama, Gensuke; Takashi, Tohru; Yokoyama, Mika; Nakayama, Atsushi; Baldwin, John J.; McDonald, Edward; Moriarty, Kevin J.; Sarko, Christopher R.; Saionz, Kurt W.; Swanson, Robert; Hussain, Zahid; Wong, Angela; MacHinaga, Nobuo Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2725 - 2746

 Synonyms

(4R)-4-Methoxy-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
(2S,4R)-4-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
1,2-Pyrrolidinedicarboxylic acid, 4-methoxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)-