3-(3,5-difluorophenyl)propanoic acid

Modify Date: 2025-08-27 16:05:47

3-(3,5-difluorophenyl)propanoic acid Structure
3-(3,5-difluorophenyl)propanoic acid structure
Common Name 3-(3,5-difluorophenyl)propanoic acid
CAS Number 84315-24-2 Molecular Weight 186.155
Density 1.3±0.1 g/cm3 Boiling Point 260.8±25.0 °C at 760 mmHg
Molecular Formula C9H8F2O2 Melting Point 59-61ºC
MSDS Chinese USA Flash Point 111.5±23.2 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 3-(3,5-Difluorophenyl)propionic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 260.8±25.0 °C at 760 mmHg
Melting Point 59-61ºC
Molecular Formula C9H8F2O2
Molecular Weight 186.155
Flash Point 111.5±23.2 °C
Exact Mass 186.049240
PSA 37.30000
LogP 1.98
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.504

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H312-H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases 21-37/38-41
Safety Phrases 26-39
RIDADR NONH for all modes of transport
HS Code 2916399090

 Synthetic Route

~99%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC Patent: WO2005/16876 A2, 2005 ; Location in patent: Page/Page column 31-32 ; WO 2005/016876 A2

~%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Tetrahedron, , vol. 63, # 2 p. 389 - 395

~%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 2403 - 2406

~85%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Brown, David S.; Marples, Brian A.; Smith, Paul; Walton, Lesley Tetrahedron, 1995 , vol. 51, # 12 p. 3587 - 3606

~%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Journal of Medicinal Chemistry, , vol. 30, # 3 p. 486 - 494

~%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Journal of Medicinal Chemistry, , vol. 30, # 3 p. 486 - 494

~%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Journal of Medicinal Chemistry, , vol. 30, # 3 p. 486 - 494

~%

3-(3,5-difluorophenyl)propanoic acid Structure

3-(3,5-difluoro...

CAS#:84315-24-2

Literature: Tetrahedron, , vol. 63, # 2 p. 389 - 395

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

Benzenepropanoic acid, 3,5-difluoro-
3,5-Difluorobenzenepropanoic acid
3,5-Difluorohydrocinnamic acid
QV2R CF EF
3-(3,5-difluorophenyl)propanoic acid
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