Solvent Yellow 5

Modify Date: 2025-09-21 11:23:00

Solvent Yellow 5 structure	Common Name	Solvent Yellow 5
	CAS Number	85-84-7	Molecular Weight	247.29500
	Density	1.173g/cm3	Boiling Point	458.035ºC at 760 mmHg
	Molecular Formula	C₁₆H₁₃N₃	Melting Point	102-104ºC
	MSDS	N/A	Flash Point	230.811ºC

Use of Solvent Yellow 5

C.I. Food Yellow 10, also known as Fast Yellow AB or Acid Yellow, is an azo dye used primarily as a food dye that is now delisted in both Europe and USA and is forbidden if used in foods and drinks. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.

Name	1-phenyldiazenylnaphthalen-2-amine
Synonym	More Synonyms

Density	1.173g/cm3
Boiling Point	458.035ºC at 760 mmHg
Melting Point	102-104ºC
Molecular Formula	C₁₆H₁₃N₃
Molecular Weight	247.29500
Flash Point	230.811ºC
Exact Mass	247.11100
PSA	50.74000
LogP	5.41860
Index of Refraction	1.647

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QM4725000

CHEMICAL NAME :: 2-Naphthylamine, 1-(phenylazo)-

CAS REGISTRY NUMBER :: 85-84-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C16-H13-N3

MOLECULAR WEIGHT :: 247.32

WISWESSER LINE NOTATION :: L66J BNUNR& CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36400 mg/kg/2Y-C

TOXIC EFFECTS :: Blood - changes in cell count (unspecified) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 45625 mg/kg/1Y-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8190 mg/kg/65W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Kidney, Ureter, Bladder - Kidney tumors

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,101,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,279,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,279,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 60,344,1955

HS Code	2927000090

benzenediazonium

CAS#:2684-02-8

Naphthalen-2-amine

CAS#:91-59-8

Solvent Yellow 5

CAS#:85-84-7

Literature: Chemische Berichte, , vol. 22, p. 1376 Chemische Berichte, , vol. 18, p. 798

Benzenediazoniu...

CAS#:100-34-5

Naphthalen-2-amine

CAS#:91-59-8

Solvent Yellow 5

CAS#:85-84-7

Literature: Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 31, # 5 p. 1040 - 1042 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 5 p. 1166 - 1168

Ethanol

CAS#:64-17-5

Naphthalen-2-amine

CAS#:91-59-8

Solvent Yellow 5

CAS#:85-84-7

Literature: Chemische Berichte, , vol. 20, p. 2896 Chemische Berichte, , vol. 18, p. 2422 Chemische Berichte, , vol. 22, p. 1376 Chemische Berichte, , vol. 18, p. 2869

benzenediazonium

CAS#:2684-02-8

Ethanol

CAS#:64-17-5

Naphthalen-2-amine

CAS#:91-59-8

Solvent Yellow 5

CAS#:85-84-7

Literature: Chemische Berichte, , vol. 20, p. 3016 Chemische Berichte, , vol. 20, p. 2896 Chemische Berichte, , vol. 22, p. 1376 Chemische Berichte, , vol. 18, p. 798

N-(1-phenyldiaz...

CAS#:10336-19-3

acetic acid

CAS#:64-19-7

Solvent Yellow 5

CAS#:85-84-7

Literature: Chemische Berichte, , vol. 18, p. 798

Precursor 5
CAS#:2684-02-8 benzenediazonium CAS#:91-59-8 Naphthalen-2-amine CAS#:100-34-5 Benzenediazoniu... CAS#:64-17-5 Ethanol
CAS#:10336-19-3 N-(1-phenyldiaz...
DownStream 8
CAS#:607-24-9 2-Nitro-1-naphthol CAS#:938-25-0 naphthalene-1,2... CAS#:215-29-2 Tribenzo[a,c,h]... CAS#:238-06-2 Acenaphtho[1,2-...
CAS#:91-59-8 Naphthalen-2-amine CAS#:108-95-2 Phenol CAS#:842-07-9 Sudan I CAS#:10336-19-3 N-(1-phenyldiaz...

HS Code	2927000090
Summary	2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: Tested for carcinogenic activity on breast after oral administration of the compound;...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL770578

Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity

Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

Name: Carcinogenic activity on ear duct after oral administration of the compound; - denote...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL771651

Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity

Name: Fluorescence polarization-based biochemical high throughput confirmation assay to ide...
Source: The Scripps Research Institute Molecular Screening Center
Target: abhydrolase domain-containing protein 4 isoform 1 [Mus musculus]
External Id: ABHD4_INH_FP_1536_3X%INH CRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

Total 105, Current Page 1 of 11

Yellow No. 2

1-phenylazonaphthalen-2-amine

1-benzeneazo-2-amino-naphthalene

2-amino-1-phenylazonaphthalene

Solvent Yellow 5

C Yellow 3

YELLOW AB

Jaune AB

C.I. Solvent Yellow 5

Dolkwal Yellow AB

Grasal Yellow

C.I. Food Yellow 10

1-phenylazo-2-aminonaphthalene

1-phenylazo-naphthalen-2-ylamine

1-phenylazo-[2]naphthylamine

Cerisol Yellow AB

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Solvent Yellow 5

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HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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Solvent Yellow 5Bioassay

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