Br-PEG4-OH

Modify Date: 2024-01-03 11:04:05

Br-PEG4-OH Structure
Br-PEG4-OH structure
Common Name Br-PEG4-OH
CAS Number 85141-94-2 Molecular Weight 257.12200
Density N/A Boiling Point N/A
Molecular Formula C8H17BrO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Br-PEG4-OH


Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-(2-(2-bromoethoxy)ethoxy)-ethoxy)ethanol
Synonym More Synonyms

 Br-PEG4-OH Biological Activity

Description Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H17BrO4
Molecular Weight 257.12200
Exact Mass 256.03100
PSA 47.92000
LogP 0.42340

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

12-bromo-3,6,9,12-tetraoxadodecan-1-ol
2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-ethanol
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