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85141-94-2

85141-94-2 structure

85141-94-2 structure

Name: Br-PEG4-OH
Chemical Name: 2-(2-(2-(2-bromoethoxy)ethoxy)-ethoxy)ethanol
CAS Number: 85141-94-2
Molecular Formula: C₈H₁₇BrO₄
Molecular Weight: 257.12200
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-12-09 08:24:58
Modify Date: 2026-07-15 11:58:50
Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(2-(2-(2-bromoethoxy)ethoxy)-ethoxy)ethanol
Synonyms	Bromo-PEG4-alcohol Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy] 12-bromo-3,6,9,12-tetraoxadodecan-1-ol Bromo-PEG4 2-[2-[2-(2-BroMoethoxy)ethoxy]ethoxy]-ethanol Br-PEG4-OH/Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy] Br-PEG4-OH, Bromo-PEG4-alcohol 2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethan-1-ol HO-PEG4-Br HO-(CH2CH2O)4-Br 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-ethanol

Description	Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₈H₁₇BrO₄
Molecular Weight	257.12200
Exact Mass	256.03100
PSA	47.92000
LogP	0.42340

Hazard Codes	Xi

Precursor 0
DownStream 1
90952-27-5

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