Pinacidil hydrate structure
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Common Name | Pinacidil hydrate | ||
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CAS Number | 85371-64-8 | Molecular Weight | 263.34 | |
Density | N/A | Boiling Point | 356.7ºC at 760 mmHg | |
Molecular Formula | C13H21N5O | Melting Point | 164-165ºC | |
MSDS | Chinese USA | Flash Point | 169.5ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Pinacidil hydratePinacidil monohydrate, an antihypertensive drug, is a potassium channel activator. |
Name | Pinacidil |
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Synonym | More Synonyms |
Description | Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator. |
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Related Catalog | |
In Vitro | Pinacidil monohydrate is a potassium channel activator[1]. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers"[2]. Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively[3]. |
References |
Boiling Point | 356.7ºC at 760 mmHg |
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Melting Point | 164-165ºC |
Molecular Formula | C13H21N5O |
Molecular Weight | 263.34 |
Flash Point | 169.5ºC |
PSA | 73.10000 |
LogP | 2.94578 |
Storage condition | 2-8℃ |
Water Solubility | ethanol: 14 mg/mL |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R22;R36/37/38 |
Safety Phrases | S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933399090 |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Evidence against a systemic arterial defect in patients with inflammatory bowel disease.
J. Surg. Res. 191(2) , 318-22, (2014) Despite increasing interest in local microvascular alterations associated with inflammatory bowel disease (IBD), the potential contribution of a primary systemic vascular defect in the etiology of IBD... |
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Kcnh2 and Kcnj8 interactively regulate skin wound healing and regeneration.
Wound Repair Regen. 23 , 797-806, (2015) Previous studies indicate that ion channels are mediators of bioelectricity promoting wound closure/regeneration in nonmammalian, lower vertebrate systems. The role of ion channels however in regenera... |
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Potassium ion channels and allergic asthma.
Adv. Exp. Med. Biol. 838 , 35-45, (2015) High-conductive calcium-sensitive potassium channels (BK+Ca) and ATP-sensitive potassium (K+ATP) channels play a significant role in the airway smooth muscle cell and goblet cell function, and cytokin... |
Pinacidil (hydrate) |
Pinacidil . monohydrate |
1-Cyano-3-(3,3-dimethylbutan-2-yl)-2-pyridin-4-ylguanidine hydrate (1:1) |
(+/-)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine |
MFCD00242745 |
Hndac |
GUANIDINE,N-CYANO-N'-4-PYRIDINYL-N''-(1,2,2-TRIMETHYLPROPYL)-, HYDRATE (1:1) |
Guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropyl)-, hydrate (1:1) |
Guanidine,N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-,monohydrate |
Pinacidil monohydrate |
EINECS 262-294-9 |
Pinacidil hydrate |
1-Cyano-2-(3,3-dimethyl-2-butanyl)-3-(4-pyridinyl)guanidine hydrate (1:1) |