10-hydroxycanthin-6-one

Modify Date: 2024-01-28 17:16:21

10-hydroxycanthin-6-one Structure
10-hydroxycanthin-6-one structure
Common Name 10-hydroxycanthin-6-one
CAS Number 86293-41-6 Molecular Weight 236.22600
Density 1.53g/cm3 Boiling Point 410.1ºC at 760mmHg
Molecular Formula C14H8N2O2 Melting Point N/A
MSDS N/A Flash Point 201.8ºC

 Use of 10-hydroxycanthin-6-one


10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent[1].

 Names

Name 10-hydroxycanthin-6-one
Synonym More Synonyms

 10-hydroxycanthin-6-one Biological Activity

Description 10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent[1].
Related Catalog
In Vitro 10-Hydroxycanthin-6-one shows antibacterial activity with a MIC of 15.62 µg/mL for B. cereus[1].
References

[1]. N Fukamiya, et al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3.

 Chemical & Physical Properties

Density 1.53g/cm3
Boiling Point 410.1ºC at 760mmHg
Molecular Formula C14H8N2O2
Molecular Weight 236.22600
Flash Point 201.8ºC
Exact Mass 236.05900
PSA 54.60000
LogP 2.14430
Index of Refraction 1.795
Water Solubility Very slightly soluble (0.61 g/L) (25 ºC)

 Synonyms

10-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one,10-hydroxy
ervine
CHEBI:66064
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