10-hydroxycanthin-6-one

Modify Date: 2025-08-27 13:26:28

10-hydroxycanthin-6-one Structure
10-hydroxycanthin-6-one structure
Common Name 10-hydroxycanthin-6-one
CAS Number 86293-41-6 Molecular Weight 236.22600
Density 1.53g/cm3 Boiling Point 410.1ºC at 760mmHg
Molecular Formula C14H8N2O2 Melting Point N/A
MSDS N/A Flash Point 201.8ºC

 Use of 10-hydroxycanthin-6-one


10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent[1].

 Names

Name 10-hydroxycanthin-6-one
Synonym More Synonyms

 10-hydroxycanthin-6-one Biological Activity

Description 10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent[1].
Related Catalog
In Vitro 10-Hydroxycanthin-6-one shows antibacterial activity with a MIC of 15.62 µg/mL for B. cereus[1].
References

[1]. N Fukamiya, et al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3.

 Chemical & Physical Properties

Density 1.53g/cm3
Boiling Point 410.1ºC at 760mmHg
Molecular Formula C14H8N2O2
Molecular Weight 236.22600
Flash Point 201.8ºC
Exact Mass 236.05900
PSA 54.60000
LogP 2.14430
Index of Refraction 1.795
InChIKey FZLISVGXWLVEPB-UHFFFAOYSA-N
SMILES O=c1ccc2nccc3c4cc(O)ccc4n1c23
Water Solubility Very slightly soluble (0.61 g/L) (25 ºC)

 Synonyms

10-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one,10-hydroxy
ervine
CHEBI:66064
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