MKI 833

Modify Date: 2025-08-25 12:35:10

MKI 833 Structure
MKI 833 structure
Common Name MKI 833
CAS Number 863029-99-6 Molecular Weight 574.13900
Density N/A Boiling Point N/A
Molecular Formula C30H32ClN7OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MKI 833


MKI 833 (Balamapimod) is a reversible Ras/Raf/MEK inhibitor with potential anti-tumor activity.

 Names

Name 4-[3-chloro-4-(1-methylimidazol-2-yl)sulfanylanilino]-6-methoxy-7-(4-pyrrolidin-1-ylpiperidin-1-yl)quinoline-3-carbonitrile
Synonym More Synonyms

 MKI 833 Biological Activity

Description MKI 833 (Balamapimod) is a reversible Ras/Raf/MEK inhibitor with potential anti-tumor activity.
Related Catalog
Target

MEK

References

[1]. Jose R. Conejo-Garcia, et al. Methods and compositions for treatment of metastatic and refractory cancers and tumors. US20170020964A1.

 Chemical & Physical Properties

Molecular Formula C30H32ClN7OS
Molecular Weight 574.13900
Exact Mass 573.20800
PSA 110.77000
LogP 5.88618

 Synthetic Route

~%

MKI 833 Structure

MKI 833

CAS#:863029-99-6

Literature: Wyeth Patent: US2005/187247 A1, 2005 ; Location in patent: Page/Page column 23 ; US 20050187247 A1

 Synonyms

4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}amino)-6-methoxy-7-(4-pyrrolidin-1-ylpiperidin-1-yl)quinoline-3-carbonitrile
MKI-833
4-({3-chloro-4-[(1-methyl-1H-imidazole-2-yl)thio]phenyl}amino)-6-methoxy-7-(4-pyrrolidin-1-ylpiperidin-1-yl)quinoline-3-carbonitrile
UNII-7Y0IV7N95Q
Balamapimod
Balamapimod (USAN)
MKI 833
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