Gsk466317a

Modify Date: 2024-01-16 11:39:22

Gsk466317a Structure
Gsk466317a structure
Common Name Gsk466317a
CAS Number 864082-48-4 Molecular Weight 448.83
Density N/A Boiling Point N/A
Molecular Formula C21H16ClF3N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gsk466317a


GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively[1].

 Names

Name GSK466317A

 Gsk466317a Biological Activity

Description GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively[1].
Related Catalog
Target

PKA:12.59 μM (IC50)

References

[1]. Homan KT, et, al. Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors. ACS Chem Biol. 2015 Jan 16;10(1):310-9.  

 Chemical & Physical Properties

Molecular Formula C21H16ClF3N4O2
Molecular Weight 448.83
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