3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine

Modify Date: 2024-01-04 14:50:43

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure
3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine structure
Common Name 3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine
CAS Number 866546-10-3 Molecular Weight 385.66300
Density 1.68g/cm3 Boiling Point 527ºC at 760 mmHg
Molecular Formula C14H10BrClN2O2S Melting Point N/A
MSDS N/A Flash Point 272.5ºC

 Names

Name 3-bromo-5-chloro-1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.68g/cm3
Boiling Point 527ºC at 760 mmHg
Molecular Formula C14H10BrClN2O2S
Molecular Weight 385.66300
Flash Point 272.5ºC
Exact Mass 383.93300
PSA 60.34000
LogP 5.07840
Index of Refraction 1.695

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~82%

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure

3-bromo-5-chlor...

CAS#:866546-10-3

Literature: VERTEX PHARMACEUTICALS INCORPORATED? Patent: WO2005/95400 A1, 2005 ; Location in patent: Page/Page column 345; 347 ; WO 2005/095400 A1

~85%

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure

3-bromo-5-chlor...

CAS#:866546-10-3

Literature: MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ; Location in patent: Page/Page column 31-32 ;

~%

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure

3-bromo-5-chlor...

CAS#:866546-10-3

Literature: MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

~%

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure

3-bromo-5-chlor...

CAS#:866546-10-3

Literature: MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

~%

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure

3-bromo-5-chlor...

CAS#:866546-10-3

Literature: MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

~%

3-bromo-5-chloro-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine Structure

3-bromo-5-chlor...

CAS#:866546-10-3

Literature: MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-bromo-5-chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine
3-bromo-5-chloro-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine
1H-Pyrrolo[2,3-b]pyridine,3-bromo-5-chloro-1-[(4-methylphenyl)sulfonyl]