1,2,4-Benzotriazin-3-amine, 7-(2-chloro-5-Methoxyphenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]
Modify Date: 2025-08-26 23:27:06
![1,2,4-Benzotriazin-3-amine, 7-(2-chloro-5-Methoxyphenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl] Structure](https://image.chemsrc.com/caspic/024/867331-63-3.png)
1,2,4-Benzotriazin-3-amine, 7-(2-chloro-5-Methoxyphenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl] structure
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Common Name | 1,2,4-Benzotriazin-3-amine, 7-(2-chloro-5-Methoxyphenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl] | ||
|---|---|---|---|---|
| CAS Number | 867331-63-3 | Molecular Weight | 489.99700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28ClN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | 7-(2-chloro-5-methoxyphenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-3-amine |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C27H28ClN5O2 |
|---|---|
| Molecular Weight | 489.99700 |
| Exact Mass | 489.19300 |
| PSA | 72.40000 |
| LogP | 5.89130 |
| InChIKey | OJBBZIACVFADED-UHFFFAOYSA-N |
| SMILES | COc1ccc(Cl)c(-c2cc(C)c3nc(Nc4ccc(OCCN5CCCC5)cc4)nnc3c2)c1 |
| Hazard Codes | Xi |
|---|
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~52%
1,2,4-Benzotria... CAS#:867331-63-3 |
| Literature: Palanki, Moorthy S. S.; Akiyama, Hideo; Campochiaro, Peter; Cao, Jianguo; Chow, Chun P.; Dellamary, Luis; Doukas, John; Fine, Richard; Gritzen, Colleen; Hood, John D.; Hu, Steven; Kachi, Shu; Kang, Xinshan; Klebansky, Boris; Kousba, Ahmed; Lohse, Dan; Chi, Ching Mak; Martin, Michael; McPherson, Andrew; Pathak, Ved P.; Renick, Joel; Soll, Richard; Umeda, Naoyasu; Yee, Shiyin; Yokoi, Katsutoshi; Zeng, Binqi; Zhu, Hong; Noronha, Glenn Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1546 - 1559 |
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~54%
1,2,4-Benzotria... CAS#:867331-63-3 |
| Literature: TargeGen, Inc. Patent: US2005/245524 A1, 2005 ; Location in patent: Page/Page column 69 ; US 20050245524 A1 |
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~%
1,2,4-Benzotria... CAS#:867331-63-3 |
| Literature: Noronha, Glenn; Barrett, Kathy; Boccia, Antonio; Brodhag, Tessa; Cao, Jianguo; Chow, Chun P.; Dneprovskaia, Elena; Doukas, John; Fine, Richard; Gong, Xianchang; Gritzen, Colleen; Gu, Hong; Hanna, Ehab; Hood, John D.; Hu, Steven; Kang, Xinshan; Key, Jann; Klebansky, Boris; Kousba, Ahmed; Li, Ge; Lohse, Dan; Mak, Chi Ching; McPherson, Andrew; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Shi, Feng; Soll, Richard; Splittgerber, Ute; Stoughton, Silva; Tang, Suhan; Yee, Shiyin; Zeng, Binqi; Zhao, Ningning; Zhu, Hong Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 602 - 608 |
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~%
1,2,4-Benzotria... CAS#:867331-63-3 |
| Literature: Noronha, Glenn; Barrett, Kathy; Boccia, Antonio; Brodhag, Tessa; Cao, Jianguo; Chow, Chun P.; Dneprovskaia, Elena; Doukas, John; Fine, Richard; Gong, Xianchang; Gritzen, Colleen; Gu, Hong; Hanna, Ehab; Hood, John D.; Hu, Steven; Kang, Xinshan; Key, Jann; Klebansky, Boris; Kousba, Ahmed; Li, Ge; Lohse, Dan; Mak, Chi Ching; McPherson, Andrew; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Shi, Feng; Soll, Richard; Splittgerber, Ute; Stoughton, Silva; Tang, Suhan; Yee, Shiyin; Zeng, Binqi; Zhao, Ningning; Zhu, Hong Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 602 - 608 |
|
~%
1,2,4-Benzotria... CAS#:867331-63-3 |
| Literature: Noronha, Glenn; Barrett, Kathy; Boccia, Antonio; Brodhag, Tessa; Cao, Jianguo; Chow, Chun P.; Dneprovskaia, Elena; Doukas, John; Fine, Richard; Gong, Xianchang; Gritzen, Colleen; Gu, Hong; Hanna, Ehab; Hood, John D.; Hu, Steven; Kang, Xinshan; Key, Jann; Klebansky, Boris; Kousba, Ahmed; Li, Ge; Lohse, Dan; Mak, Chi Ching; McPherson, Andrew; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Shi, Feng; Soll, Richard; Splittgerber, Ute; Stoughton, Silva; Tang, Suhan; Yee, Shiyin; Zeng, Binqi; Zhao, Ningning; Zhu, Hong Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 602 - 608 |
![7-(2-CHLORO-5-METHOXYPHENYL)-5-METHYLBENZO[E][1,2,4]TRIAZIN-3-AMINE structure](https://image.chemsrc.com/caspic/201/867330-72-1.png)
![1-[2-(4-Bromophenoxy)ethyl]pyrrolidine structure](https://image.chemsrc.com/caspic/084/1081-73-8.png)
CAS#:867334-05-2|
Name: Inhibition of human recombinant c-Src using PTK2 substrate incubated for 90 mins by l...
Source: ChEMBL
Target: Proto-oncogene tyrosine-protein kinase Src
External Id: CHEMBL3883087
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Name: Inhibition of Src
Source: ChEMBL
Target: Proto-oncogene tyrosine-protein kinase Src
External Id: CHEMBL905921
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Name: Luciferase-Based Assay from US Patent US8481536: "Benzotriazine inhibitors of kinases...
Source: BindingDB
Target: N/A
External Id: BindingDB_5868_1
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| 7-(2-chloro-5-methoxyphenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-3-ylamine |
| [7-(2-chloro-5-methoxy-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine |
| 7-(2-chloro-5-methoxyphenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine |