ICI141292

Modify Date: 2024-01-20 13:41:04

ICI141292 Structure
ICI141292 structure
Common Name ICI141292
CAS Number 86880-51-5 Molecular Weight 369.41400
Density 1.28g/cm3 Boiling Point 689.7ºC at 760mmHg
Molecular Formula C20H23N3O4 Melting Point N/A
MSDS N/A Flash Point 370.9ºC

 Use of ICI141292


ICI141292 is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.

 Names

Name N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide
Synonym More Synonyms

 ICI141292 Biological Activity

Description ICI141292 is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
Related Catalog
Target

β1 adrenoceptor[1]

In Vitro ICI141292 (Epanolol) is a novel anti-anginal agent which is a β1-adrenoceptor partial agonist exhibiting selective β1-adrenoceptor antagonist and selective β1-adrenoceptor agonist activity[1].
References

[1]. Hosie J, et al. Pharmacokinetics of epanolol after acute and chronic oral dosing in elderly patients with stable angina pectoris. Br J Clin Pharmacol. 1990 Mar;29(3):333-7.

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 689.7ºC at 760mmHg
Molecular Formula C20H23N3O4
Molecular Weight 369.41400
Flash Point 370.9ºC
Exact Mass 369.16900
PSA 114.61000
LogP 1.73388
Index of Refraction 1.617

 Synonyms

Epanololum [Latin]
(+-)-N-(2-((3-(o-Cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-2-(p-hydroxyphenyl)acetamide
Visacor
Epanololum
Benzeneacetamide,N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxy
Epanolol
ICI141292
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