H-Gly-Leu-OH

Modify Date: 2025-08-22 09:21:52

H-Gly-Leu-OH Structure
H-Gly-Leu-OH structure
 Common Name H-Gly-Leu-OH
CAS Number 869-19-2 Molecular Weight 188.224
Density 1.1±0.1 g/cm3 Boiling Point 410.4±30.0 °C at 760 mmHg
Molecular Formula C8H16N2O3 Melting Point 233-235 °C(lit.)
MSDS N/A Flash Point 202.0±24.6 °C

 Use of H-Gly-Leu-OH


Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.

 Names

Name N-Glycyl-L-leucine
Synonym More Synonyms

 H-Gly-Leu-OH Biological Activity

Description Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.
Related Catalog
References

[1]. Ganapathy V, et al. Interaction of amino acids with glycl-L-leucine hydrolysis and transport in monkey small intestine. Clin Sci (Lond). 1979 Dec;57(6):521-7.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 410.4±30.0 °C at 760 mmHg
Melting Point 233-235 °C(lit.)
Molecular Formula C8H16N2O3
Molecular Weight 188.224
Flash Point 202.0±24.6 °C
Exact Mass 188.116089
PSA 92.42000
LogP -0.09
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.489
InChIKey DKEXFJVMVGETOO-LURJTMIESA-N
SMILES CC(C)CC(NC(=O)CN)C(=O)O
Storage condition -20°C

 Safety Information

Hazard Codes Xi
Safety Phrases S24/25
WGK Germany 3
HS Code 2924199090

 Synthetic Route

methyl L-leucinate structure

methyl L-leucinate

CAS#:2666-93-5

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Journal of the American Chemical Society, , vol. 74, p. 3818,3819
L-leucine structure

L-leucine

CAS#:61-90-5

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Nippon Nogei Kagaku Kaishi, , vol. 28, p. 672 Chem.Abstr., , p. 7526
L-Leucine,N-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]- (9CI) structure

L-Leucine,N-[(1...

CAS#:6707-71-7

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Nippon Nogei Kagaku Kaishi, , vol. 28, p. 672 Chem.Abstr., , p. 7526 Journal of Biological Chemistry, , vol. 212, p. 973,975
methyl L-leucinate structure

methyl L-leucinate

CAS#:2666-93-5

benzyl N-(2-chloro-2-oxoethyl)carbamate structure

benzyl N-(2-chl...

CAS#:15050-24-5

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Journal of Organic Chemistry, , vol. 15, p. 108,115
N/A structure

N/A

CAS#:1478-70-2

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Chemische Berichte, , vol. 92, p. 2095,2098
Z-Gly-Leu-OH structure

Z-Gly-Leu-OH

CAS#:1421-69-8

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 580, p. 68,78
Cbz-glycylleucine ethyl ester structure

Cbz-glycylleuci...

CAS#:7352-21-8

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 580, p. 68,78
glycyl=>glycyl=>leucine structure

glycyl=>glycyl=...

CAS#:144732-62-7

~%

H-Gly-Leu-OH Structure

H-Gly-Leu-OH

CAS#:869-19-2

Glycine structure

Glycine

CAS#:56-40-6

Literature: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 175, p. 30

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 H-Gly-Leu-OHBioassay

View more

Name: Activation of human PEPT1 expressed in MDCK cells
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863210
Name: Activation of human PEPT1 expressed in MDCK cells relative to Gly-Sar
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863211
Name: Bitter threshold value
Source: ChEMBL
Target: N/A
External Id: CHEMBL848034
Name: Activation of nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid up...
Source: ChEMBL
Target: General amino-acid permease GAP1
External Id: CHEMBL1228070
Name: TP_TRANSPORTER: inhibition of Ceftibuten uptake (Ceftibuten: 1000 uM, Gly-Leu: 10000 ...
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL2075948
Name: Ratio of %GSmax to EC50 for human PEPT1 activation
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863212
Name: Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK...
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL863213
Name: Partition coefficient (logP)
Source: ChEMBL
Target: N/A
External Id: CHEMBL636806
Name: TP_TRANSPORTER: inhibition of Ceftibuten uptake (Ceftibuten: 1000 uM, Gly-Leu: 10000 ...
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL2075949
Name: TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells
Source: ChEMBL
Target: Solute carrier family 15 member 2
External Id: CHEMBL2076211
Total 20, Current Page 1 of 2
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 Synonyms

Gly-L-Leu-OH
EINECS 212-785-9
Gly-Leu
L-Leucine,N-glycyl
Glycinyl-l-leucine
Glycyl-L-leucine
Glycylleucine
(2S)-2-[(Aminoacetyl)amino]-4-methylpentanoic acid
(E)-N-(2-Amino-1-hydroxyethylidene)-L-leucine
GLY-L-LEU
MFCD00008127
H-GLY-LEU-OH
N-Glycylleucine
L-Leucine,glycyl
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