4-(Hydroxymethyl)benzonitrile

Modify Date: 2026-07-01 09:09:22

4-(Hydroxymethyl)benzonitrile Structure
4-(Hydroxymethyl)benzonitrile structure
Common Name 4-(Hydroxymethyl)benzonitrile
CAS Number 874-89-5 Molecular Weight 133.147
Density 1.2±0.1 g/cm3 Boiling Point 297.4±23.0 °C at 760 mmHg
Molecular Formula C8H7NO Melting Point 39-43ºC(lit.)
MSDS Chinese USA Flash Point 133.6±22.6 °C
Symbol GHS07
GHS07
Signal Word Warning

Summary: 4-(Hydroxymethyl)benzonitrile, also known as 4-(羟甲基)苯甲腈, Chinese name: 羟甲基, CAS number: 874-89-5, molecular formula: C8H7NO, molecular weight: 133.147. Melting point: 39-43ºC, boiling point: 297.4±23.0 °C, density: 1.2±0.1 g/cm³. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 4-(Hydroxymethyl)benzonitrile
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.2±0.1 g/cm3
Boiling Point 297.4±23.0 °C at 760 mmHg
Melting Point 39-43ºC(lit.)
Molecular Formula C8H7NO
Molecular Weight 133.147
Flash Point 133.6±22.6 °C
Exact Mass 133.052765
PSA 44.02000
LogP 0.47
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.572
InChIKey XAASLEJRGFPHEV-UHFFFAOYSA-N
SMILES N#Cc1ccc(CO)cc1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 4-(Hydroxymethyl)benzonitrile
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
H312:Harmful in contact with skin
H315:Causes skin irritation
H319:Causes serious eye irritation
Harmful if inhaled
H332:
H335:May cause respiratory irritation
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:4-(Hydroxymethyl)benzonitrile
CAS number:874-89-5

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C8H7NO
Molecular weight: 133.1

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN3439Class: 6.1Packing group: III
Proper shipping name: NITRILES, TOXIC, SOLID, N.O.S. (4-(Hydroxymethyl)benzonitrile)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases 26-36
RIDADR UN 3439
WGK Germany 3.0
HS Code 2926909090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles3

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Vinyl monomers bearing chromophore moieties and their polymers. VIII. synthesis and fluorescence behavior of a vinyloxy monomer having an electron-accepting chromophore moiety, p-((vinyloxy) methyl) benzonitrile, and its polymers. Du FS, et al.

J. Polym. Sci. A Polym. Chem. 37(2) , 179-187, (1999)

Bu4N [Fe (CO)3(NO)]-Catalyzed Hydrosilylation of Aldehydes and Ketones. Dieskau AP, et al.

European J. Org. Chem. 27 , 5291-5296, (2011)

Bergsträßer U, et al.

Science of Synthesis: Houben-Weyl Methods of Molecular Transformations , (2014), 219

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00870633
4-(Hydroxymethyl)benzonitrile

 4-(Hydroxymethyl)benzonitrile | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the safety information for 4-(Hydroxymethyl)benzonitrile?
A: Safety information for 4-(Hydroxymethyl)benzonitrile: 26-36.
Q: What is the molecular formula of 4-(Hydroxymethyl)benzonitrile?
A: Molecular formula of 4-(Hydroxymethyl)benzonitrile is C8H7NO.
Q: What are the downstream products of 4-(Hydroxymethyl)benzonitrile?
A: Related downstream products(CAS) of 4-(Hydroxymethyl)benzonitrile: 5462-71-5;6068-72-0;39895-56-2;17930-02-8;21388-95-4;18693-97-5;24167-50-8;3034-34-2;187283-17-6;3006-96-0.
Q: What is the boiling point of 4-(Hydroxymethyl)benzonitrile?
A: Boiling point of 4-(Hydroxymethyl)benzonitrile is 297.4±23.0 °C at 760 mmHg.
Q: What is the LogP of 4-(Hydroxymethyl)benzonitrile?
A: LogP of 4-(Hydroxymethyl)benzonitrile is 0.47.
Q: What are the upstream materials of 4-(Hydroxymethyl)benzonitrile?
A: Related upstream materials(CAS) of 4-(Hydroxymethyl)benzonitrile: 619-65-8;105-07-7;873-75-6;143-33-9;10406-25-4;1236144-52-7;1129-35-7;39895-56-2;952-92-1.
Q: What is the molecular weight of 4-(Hydroxymethyl)benzonitrile?
A: Molecular weight of 4-(Hydroxymethyl)benzonitrile is 133.147.
Q: What is the English name of 4-(Hydroxymethyl)benzonitrile?
A: The English name of 4-(Hydroxymethyl)benzonitrile is 4-(Hydroxymethyl)benzonitrile.
Q: What is the melting point of 4-(Hydroxymethyl)benzonitrile?
A: Melting point of 4-(Hydroxymethyl)benzonitrile is 39-43ºC(lit.).
Q: What English synonyms does 4-(Hydroxymethyl)benzonitrile have?
A: English synonyms of 4-(Hydroxymethyl)benzonitrile: MFCD00870633, 4-(Hydroxymethyl)benzonitrile.

 4-(Hydroxymethyl)benzonitrilefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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