(-)-Denudatin B

Modify Date: 2024-07-18 16:04:02

(-)-Denudatin B structure	Common Name	(-)-Denudatin B
	CAS Number	87402-88-8	Molecular Weight	356.41
	Density	1.2±0.1 g/cm3	Boiling Point	491.1±45.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	214.2±28.8 °C

Use of (-)-Denudatin B

(-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action

Name	Denudatin B
Synonym	More Synonyms

Description	(-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cardiovascular Disease
References	[1]. Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47. [2]. Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130.

Description

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Cardiovascular Disease

References

[1]. Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47.

[2]. Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130.

Density	1.2±0.1 g/cm3
Boiling Point	491.1±45.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₄O₅
Molecular Weight	356.41
Flash Point	214.2±28.8 °C
Exact Mass	356.162384
PSA	53.99000
LogP	2.87
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.565