3'-Hydroxy Repaglinide

Modify Date: 2024-01-10 23:53:04

3'-Hydroxy Repaglinide structure	Common Name	3'-Hydroxy Repaglinide
	CAS Number	874908-14-2	Molecular Weight	468.58500
	Density	1.186g/cm3	Boiling Point	709.6ºC at 760 mmHg
	Molecular Formula	C₂₇H₃₆N₂O₅	Melting Point	79-82ºC
	MSDS	N/A	Flash Point	383ºC

Use of 3'-Hydroxy Repaglinide

3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].

Name	2-ethoxy-4-[2-[[1-[2-(3-hydroxypiperidin-1-yl)phenyl]-3-methylbutyl]amino]-2-oxoethyl]benzoic acid

Description	3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268. [2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.

Description

Related Catalog

Research Areas >> Metabolic Disease

References

[1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268.

[2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.

Density	1.186g/cm3
Boiling Point	709.6ºC at 760 mmHg
Melting Point	79-82ºC
Molecular Formula	C₂₇H₃₆N₂O₅
Molecular Weight	468.58500
Flash Point	383ºC
Exact Mass	468.26200
PSA	102.59000
LogP	5.09600
Index of Refraction	1.581
Storage condition	-20°C

DC Chemicals Limited
China
Product Name: 3'-Hydroxy Repaglinide
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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