6-Hydroxyrubiadin

Modify Date: 2024-01-09 20:22:07

6-Hydroxyrubiadin Structure
6-Hydroxyrubiadin structure
Common Name 6-Hydroxyrubiadin
CAS Number 87686-86-0 Molecular Weight 270.237
Density 1.6±0.1 g/cm3 Boiling Point 558.7±19.0 °C at 760 mmHg
Molecular Formula C15H10O5 Melting Point N/A
MSDS N/A Flash Point 305.7±18.0 °C

 Use of 6-Hydroxyrubiadin


6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1].

 Names

Name 6-Hydroxyrubiadin
Synonym More Synonyms

 6-Hydroxyrubiadin Biological Activity

Description 6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1].
Related Catalog
In Vitro 6-hydroxyrubiadin suppresses lipopolysaccharide (LPS)-induced nuclear factor-kappa B activation as well as the phosphorylation of c-Jun N-terminal kinase in RAW 264.7 macrophages[1]. 6-hydroxyrubiadin inhibited the expression of tumor necrosis factor (TNF)-a, interleukin (IL)-1b and IL-6 in phorbol myristate acetate (PMA)-primed U937 and RAW 264.7cells[1].
In Vivo 6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model[1].
References

[1]. Yanting Wu, et al. In vitro and in vivo inhibitory effects of 6-hydroxyrubiadin on lipopolysaccharide-induced inflammation. Immunopharmacol Immunotoxicol. 2017 Jun;39(3):107-116.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 558.7±19.0 °C at 760 mmHg
Molecular Formula C15H10O5
Molecular Weight 270.237
Flash Point 305.7±18.0 °C
Exact Mass 270.052826
PSA 94.83000
LogP 4.42
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.745

 Safety Information

Hazard Codes Xi

 Synonyms

1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone
1,3,6-trihydroxy-2-methylanthracene-9,10-dione
9,10-Anthracenedione, 1,3,6-trihydroxy-2-methyl-
2-Methyl-1,3,6-trihydroxyanthraquinone