WRW4 TFA structure
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Common Name | WRW4 TFA | ||
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CAS Number | 878557-55-2 | Molecular Weight | 1104.27000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C61H65N15O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of WRW4 TFAWRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide[1]. |
Name | L-Tryptophanamide, L-tryptophyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-tryptophyl |
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Synonym | More Synonyms |
Description | WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide[1]. |
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Related Catalog | |
In Vitro | WRW4 inhibits Abeta42 peptide-induced superoxide generation and chemotactic migration of neutrophils, and also completely inhibits the internalization of Abeta42 peptide in human macrophages. WRW4 specifically blocks ERK phosphorylation downstream of FPRL1 by WKYMVm[1]. |
References |
Molecular Formula | C61H65N15O6 |
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Molecular Weight | 1104.27000 |
Exact Mass | 1103.52000 |
PSA | 355.46000 |
LogP | 8.65230 |
Storage condition | -20℃ |
NPEC-caged-noradrenalin |