TBMP

Modify Date: 2024-01-08 19:17:27

TBMP Structure
TBMP structure
 Common Name TBMP
CAS Number 88-32-4 Molecular Weight 180.24
Density 1.009 g/cm3 Boiling Point 293.3ºC at 760 mmHg
Molecular Formula C11H16O2 Melting Point 64℃
MSDS N/A Flash Point 136ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Use of TBMP


3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system[1][2].

 Names

Name 2-tert-butyl-4-hydroxyanisole
Synonym More Synonyms

 TBMP Biological Activity

Description 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system[1][2].
Related Catalog
References

[1]. Lam LK, et al. Effects of 2- and 3-tert-butyl-4-hydroxyanisole on glutathione S-transferase and epoxide hydrolase activities and sulfhydryl levels in liver and forestomach of mice. Cancer Res. 1981 Oct;41(10):3940-3.  

[2]. Insecticide for vermin of order coleoptera. Japan, JP55136202 A 1980-10-23.

 Chemical & Physical Properties

Density 1.009 g/cm3
Boiling Point 293.3ºC at 760 mmHg
Melting Point 64℃
Molecular Formula C11H16O2
Molecular Weight 180.24
Flash Point 136ºC
Exact Mass 180.11500
PSA 29.46000
LogP 2.69830
Index of Refraction 1.507

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SK1575010
CHEMICAL NAME :
Phenol, 3-tert-butyl-4-methoxy-
CAS REGISTRY NUMBER :
88-32-4
BEILSTEIN REFERENCE NO. :
2209222
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H16-O2
MOLECULAR WEIGHT :
180.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
27 gm/kg/3W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 76,143,1986

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xn
Risk Phrases 22-36
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

2-tert-butyl-1,4-dimethoxybenzene structure

2-tert-butyl-1,...

CAS#:21112-37-8

~67%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: Synthesis, , # 8 p. 638 - 640
tert-Butylhydroquinone structure

tert-Butylhydro...

CAS#:1948-33-0

~%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: Journal of Medicinal Chemistry, , vol. 22, # 5 p. 569 - 571
Dimethyl sulfate structure

Dimethyl sulfate

CAS#:77-78-1

tert-Butylhydroquinone structure

tert-Butylhydro...

CAS#:1948-33-0

~%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: WO2007/15260 A2, ; Page/Page column 7-9 ;
tert-butyl(3-(tert-butyl)-4-methoxyphenoxy)dimethylsilane structure

tert-butyl(3-(t...

CAS#:70020-84-7

~%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: Journal of Medicinal Chemistry, , vol. 22, # 5 p. 569 - 571
2-(tert-butyl)-4-((tert-butyldimethylsilyl)oxy)phenol structure

2-(tert-butyl)-...

CAS#:70020-83-6

~%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: Journal of Medicinal Chemistry, , vol. 22, # 5 p. 569 - 571
Mequinol structure

Mequinol

CAS#:150-76-5

tert-Butanol structure

tert-Butanol

CAS#:75-65-0

~%

2-tert-Butyl-4-methoxyphenol structure

2-tert-Butyl-4-...

CAS#:121-00-6

TBMP Structure

TBMP

CAS#:88-32-4

Literature: US2616931 , ;
2,5-DI-TERT-BUTYL-4-HYDROXYANISOLE structure

2,5-DI-TERT-BUT...

CAS#:1991-52-2

~%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: US2792427 , ;
Mequinol structure

Mequinol

CAS#:150-76-5

Isobutylene structure

Isobutylene

CAS#:115-11-7

~%

TBMP Structure

TBMP

CAS#:88-32-4

Literature: Fette und Seifen, , vol. 57, p. 656,658
2,5-DI-TERT-BUTYL-4-HYDROXYANISOLE structure

2,5-DI-TERT-BUT...

CAS#:1991-52-2

~%

2-tert-Butyl-4-methoxyphenol structure

2-tert-Butyl-4-...

CAS#:121-00-6

TBMP Structure

TBMP

CAS#:88-32-4

Mequinol structure

Mequinol

CAS#:150-76-5

Literature: US2792427 , ; US2676191 , ;

 Customs

HS Code 2909500000
Summary 2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles14

More Articles
Modulation by dietary factors of BHA-induced alterations in cell kinetics of gastro-intestinal tract tissues in rats.

Food Chem. Toxicol. 29(2) , 79-85, (1991)

To determine the effects of dietary ethanol or fibre on 2(3)-tert-butyl-4-hydroxyanisole (BHA)-induced alterations in cell kinetics in gastro-intestinal tract tissues, groups of six male Wistar rats w...

Antioxidant properties of melatonin: a pulse radiolysis study.

Free Radic. Biol. Med. 26(5-6) , 557-65, (1999)

Various one-electron oxidants such as OH*, tert-BuO*, CCl3OO*, Br2*- and N3*, generated pulse radiolytically in aqueous solutions at pH 7, were scavenged by melatonin to form two main absorption bands...

Chemoprevention of cancer: phenolic antioxidants (BHT, BHA).

Int. J. Biochem. 20(7) , 639-51, (1988)

1. The synthetic phenolic antioxidants (e.g. BHT, BHA) added to human and animal food are able to lengthen the life of organisms and lower the incidence of cancer caused by chemical compounds. 2. On t...

 Synonyms

2-TERT-BUTYL-4-HYDROXYANISOLE
4-Methoxy-3-te
2-BHA
3-tert-Bha
2-TERT-BUTYLHYDROXYANISOLE
3-tert-butyl-4-methoxy-pheno
2-T-BUTYL-4-HYDROXYANISOLE
3-TERT-BUTYL-4-METHOXYPHENOL
4-Methoxy-3
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Chemsrc provides TBMP(CAS#:88-32-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TBMP are included as well.>> amp version: TBMP

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