CNT2 inhibitor-1
Modify Date: 2024-01-08 17:47:43
CNT2 inhibitor-1 structure
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Common Name | CNT2 inhibitor-1 | ||
|---|---|---|---|---|
| CAS Number | 880155-70-4 | Molecular Weight | 448.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H24N6O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CNT2 inhibitor-1CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. |
| Name | CNT2 inhibitor-1 |
|---|
| Description | CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. |
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| Related Catalog | |
| Target |
IC50: 640 nM (hCNT2)[1][2]. |
| In Vitro | CNT2 inhibitor-1 (compound 48) exhibits 81-fold more potent inhibitory activity than the parent compound 12. In addition, CNT2 inhibitor-1 exhibits inhibitory activity 1500-fold more potent than that of 2’-deoxy-5-fluorouridine, phlorizin, and 7,8,3’-trihydroxyflavone, which are well-known hCNT2 inhibitors[1]. CNT2 inhibitor-1 (compound 1) is a potent inhibitor with poor solubility[2]. |
| References |
| Molecular Formula | C23H24N6O4 |
|---|---|
| Molecular Weight | 448.47 |
| Storage condition | 2-8℃ |