URAT1 inhibitor 1

Modify Date: 2024-01-09 16:24:57

URAT1 inhibitor 1 Structure
URAT1 inhibitor 1 structure
Common Name URAT1 inhibitor 1
CAS Number 2268720-62-1 Molecular Weight 569.29
Density N/A Boiling Point N/A
Molecular Formula C19H15Br2N5O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of URAT1 inhibitor 1


URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1].

 Names

Name URAT1 inhibitor 1

 URAT1 inhibitor 1 Biological Activity

Description URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1].
Related Catalog
Target

IC50: 32 nM (URAT1)[1].

References

[1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388.

 Chemical & Physical Properties

Molecular Formula C19H15Br2N5O2S2
Molecular Weight 569.29

 Safety Information

Hazard Codes Xi